Publications - Published papers
Please find below publications of our group. Currently, we list 565 papers. Some of the publications are in collaboration with the group of Sonja Prohaska and are also listed in the publication list for her individual group. Access to published papers (
) is restricted to our local network and chosen collaborators.
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) is restricted to our local network and chosen collaborators.
If you have problems accessing electronic information, please let us know:©NOTICE: All papers are copyrighted by the authors; If you would like to use all or a portion of any paper, please contact the author.
Robustness of Boolean dynamics under knockouts
Gunnar Boldhaus, Nils Bertschinger, Johannes Rauh, Eckehard Olbrich, Konstantin Klemm
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Status: Published
Phys. Rev E 82:021916 (2010)
Abstract
The response to a knockout of a node is a characteristic feature of a networked
dynamical system. Knockout resilience in the dynamics of the remaining nodes is
a sign of robustness. Here we study the effect of knockouts for binary state
sequences and their implementations in terms of Boolean threshold networks.
Besides random sequences with biologically plausible constraints, we analyze
the cell cycle sequence of the species Saccharomyces cerevisiae and the
Boolean networks implementing it. Comparing with an appropriate null model we do
not find evidence that the yeast wildtype network is optimized for high
knockout resilience. Our notion of knockout resilience weakly correlates with
the size of the basin of attraction, which has also been considered a measure of
robustness.