Publications - Published papers
Please find below publications of our group. Currently, we list 565 papers. Some of the publications are in collaboration with the group of Sonja Prohaska and are also listed in the publication list for her individual group. Access to published papers () is restricted to our local network and chosen collaborators.
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Evolution of the Long Non-coding RNAs MALAT1 and MENβ/ε
Peter F. Stadler
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Status: Published
In: <em>Advances in Bioinformatics and Computational Biology</em>,<br> Carlos E. Ferreira, Satoru Miyano, Peter F. Stadler (eds.), <br>Springer, Heidelberg, Lect. Notes Comp. Sci. 6268 (2010), pp.1-12<br>
Abstract
MALAT1 is one of the best-conserved long ncRNAs in mammals and shares
several characteristics, among them nuclear retention and a non-standard
processing of its 3' end, with the longer, but less well conserved,
adjacent MEN-beta RNA. We show that MALAT1 is conserved among
gnathostomes (with the possible exception of birds), while MEN-beta
likely originated in the mammalian stem lineage. Evolutionary conserved
features of both transcripts are discussed, including RNA secondary
structure motifs and short RNA processing products.
Keywords
MALAT1, MEN$\beta$, VINC, NEAT1, TncRNA