Publications - Published papers
Please find below publications of our group. Currently, we list 565 papers. Some of the publications are in collaboration with the group of Sonja Prohaska and are also listed in the publication list for her individual group. Access to published papers () is restricted to our local network and chosen collaborators.
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©NOTICE: All papers are copyrighted by the authors; If you would like to use all or a portion of any paper, please contact the author.
Multidimensional segmentation of heterogeneous data
H. S. Saker, and P. F. Stadler, and A. M. Shahin,
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PREPRINT 18-043:
Status: Published
2017 Fourth International Conference on Advances in Biomedical Engineering (ICABME)
Abstract
High-throughput methods are producing an ever increasing flood of-omics data that yield a more and more detailed and rich genomic annotation. Combining these data into coherently behaving regions lies at the heart of functional genome annotation efforts. The segmentation problem, which addresses the task of subdividing an ordered sequence of data into homogeneous, approximately constant intervals, therefore has rapidly gained practical importance in computational biology, with a strong emphasis on multi-dimensional data tracks. We suggest a new segmentation method based on decomposition thresholding, and local optimum differentiation, which detects significant breakpoints in the data to identify segment boundaries.