Publications - Published papers
Please find below publications of our group. Currently, we list 565 papers. Some of the publications are in collaboration with the group of Sonja Prohaska and are also listed in the publication list for her individual group. Access to published papers (
) is restricted to our local network and chosen collaborators.
If you have problems accessing electronic information, please let us know:
) is restricted to our local network and chosen collaborators.
If you have problems accessing electronic information, please let us know:©NOTICE: All papers are copyrighted by the authors; If you would like to use all or a portion of any paper, please contact the author.
Duplicated RNA Genes in Teleost Fish Genomes
Dominic Rose, Julian Jöris, Jörg Hackermüller, Kristin Reiche, Qiang LI, Peter F. Stadler
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Status: Published
J Bioinform Comput Biol. 2008 Dec;6(6):1157-75.
Abstract
Teleost fishes share a duplication of their entire genomes. We report here
on a computational survey of structured non-coding RNAs in teleost genomes,
focussing on the fate of fish-specific duplicates. As in other metazoan
groups we find evidence for a large number (11,543) of structured RNAs,
most of which (~86%) are clade-specific or evolve so fast that
their tetrapod homologs cannot be detected. In surprising contrast to
protein-coding genes, the fish-specific genome duplication did not lead to
a large number of paralogous ncRNAs: only 188 candidates, mostly
microRNAs, appear in a larger copy number in teleosts than in tetrapods
suggesting that large-scale gene duplications do not play a major role in
the expansion of the vertebrate ncRNA inventory.
Keywords
non-coding RNA, ncRNA, ncRNA evolution, ncRNA gene finding, RNA, teleost fish, teleosts, <i>Takifugu rubripes</i>, whole-genome duplication, comparative genomics, annotation