Publications - Published papers
Please find below publications of our group. Currently, we list 565 papers. Some of the publications are in collaboration with the group of Sonja Prohaska and are also listed in the publication list for her individual group. Access to published papers (
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©NOTICE: All papers are copyrighted by the authors; If you would like to use all or a portion of any paper, please contact the author.
Comparative Analysis of Cyclic Sequences: Viroids and other Small Circular RNAs
Axel Mosig, Ivo L. Hofacker, Peter F. Stadler
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Status: Published
Proceedings GCB 2006, Lecture Notes in Informatics P-83: 93-102 (2006)
Abstract
The analysis of small circular sequences requires specialized tools. While the differences between linear and circular sequences can be neglected in the case of long molecules such as bacterial genomes since in practice all analysis is performed in sequence windows, this is not true for viroids and related sequences which are usually only a few hundred basepairs long. In this contribution we present basic algorithms and corresponding software for circular RNAs. In particular, we discuss the problem of pairwise and multiple cyclic sequence alignments with affine gap costs, and an extension of a recent approach to circular RNA folding to the computation of consensus structures.
Keywords
RNA secondary structure, circular RNA, dynamic programming, viroids