Publications - Published papers
Please find below publications of our group. Currently, we list 565 papers. Some of the publications are in collaboration with the group of Sonja Prohaska and are also listed in the publication list for her individual group. Access to published papers (
) is restricted to our local network and chosen collaborators.
If you have problems accessing electronic information, please let us know:
) is restricted to our local network and chosen collaborators.
If you have problems accessing electronic information, please let us know:©NOTICE: All papers are copyrighted by the authors; If you would like to use all or a portion of any paper, please contact the author.
Memory Efficient Folding Algorithms for Circular RNA Secondary Structures
Ivo L. Hofacker, Peter F. Stadler
Download
Status: Published
Bioinformatics 22: 1172-1176 (2006)
Abstract
A small class of RNA molecules, in particular the tiny genomes of viroids, are circular. Yet most structure prediction algorithms handle only linear RNAs. The most straightforward approach is to compute circular structures from "internal" and "external" substructures separated by a base pair. This is incompatible, however, with the memory-saving approach of the Vienna RNA Package which builds a linear RNA structure from shorter (internal) structures only. Here we describe how circular secondary structures can be obtained without additional memory requirements as a kind of "post-processing" of the linear structures.
Keywords
RNA secondary structure, circular RNA, dynamic programming, viroids
Note
Earlier Version in: German Conference on Bioinformatics 2005, pp. 15-25; A. Torda, S. Kurtz, M. Rarey (eds.), LNI P-71 Gesellschaft f. Informatik, Bonn, 2005.