Overview on processed synteny regions for HOXA9_ENSG00000078399_5e5.protein.info
Rank | AlnOverview | AlnScore | RatioSum | logRatioSum | focalRatioSum | TargetGenome | chr | startPos | endPos | hitsCount | queryCov | meanIdentity | ori | score | compara |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 4073 | 13.08 | 3.29 | 3.66 | Danio_rerio | 16 | 15965005 | 15966531 | 2 | 99.6% | 48.9% | -1 | 226.96 | noComparaHits: hoxa9b | |
2 | 5581 | 14.73 | 2.58 | 3.63 | Danio_rerio | 19 | 10511297 | 10512339 | 2 | 63.2% | 58% | 1 | 181.55 | noComparaHits: hoxa9a | |
3 | 2119 | 4.66 | -0.39 | 1.12 | Danio_rerio | 12 | |||||||||
4 | 1490 | 2.62 | -0.4 | 0.79 | Danio_rerio | 11 | |||||||||
5 | 596 | 0.48 | -0.72 | 0.05 | Danio_rerio | 23 | |||||||||
6 | 3269 | 6.38 | -0.74 | 2.52 | Danio_rerio | 9 | 1948806 | 1949904 | 2 | 99.6% | 48% | -1 | 239.99 | noComparaHits: hoxd9a | |
7 | 4690 | 10.53 | -0.76 | 3.29 | Danio_rerio | 3 | 23033313 | 23036568 | 2 | 82.7% | 54.2% | 1 | 212.88 | noComparaHits: hoxb9a | |
8 | 204 | 0.33 | -1.1 | 0.05 | Danio_rerio | 24 | |||||||||
9 | 3322 | 7.54 | -1.98 | 3.02 | Danio_rerio | 23 | 33742961 | 33744781 | 2 | 98.5% | 49.6% | 1 | 238.58 | noComparaHits: hoxc9a | |
10 | 3318 | 7.54 | -1.98 | 3.02 | Danio_rerio | 23 | 35245651 | 35247471 | 2 | 98.5% | 49.6% | -1 | 238.58 | noComparaHits: hoxc9a |
Data table for reference protein loci
QueryProtein(s)=ENSP00000343619 (contained in p11)QueryGenome=Homo_sapiens
ref-loci | geneName | protID | transID | geneID | protName | chr | startPos | endPos | meanPos | ori | numExons | protLength | selfscore |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
p1 | SKAP2 | ENSP00000005587 | ENST00000345317 | ENSG00000005020 | SKAP2_HUMAN | 7 | 26676244 | 26870573 | 26733074 | -1 | 12 | 359 | 747.13 |
p2 | - | ENSP00000328286 | ENST00000333401 | ENSG00000184579 | - | 7 | 26988911 | 26989532 | 26989233 | -1 | 2 | 198 | 336.79 |
p3 | HOXA1 | ENSP00000343246 | ENST00000343060 | ENSG00000105991 | HXA1_HUMAN | 7 | 27100584 | 27102056 | 27101547 | -1 | 2 | 335 | 615.59 |
p4 | HOXA2 | ENSP00000222718 | ENST00000222718 | ENSG00000105996 | HXA2_HUMAN | 7 | 27106870 | 27108644 | 27107431 | -1 | 2 | 376 | 679.66 |
p5 | HOXA3 | ENSP00000324884 | ENST00000317201 | ENSG00000105997 | HXA3_HUMAN | 7 | 27114059 | 27116784 | 27114719 | -1 | 2 | 443 | 525.69 |
p6 | Q96MZ3_HUMAN | ENSP00000297027 | ENST00000297027 | ENSG00000164519 | Q96MZ3_HUMAN | 7 | 27122158 | 27128119 | 27122347 | 1 | 2 | 128 | 207.82 |
p7 | HOXA4 | ENSP00000353151 | ENST00000360046 | ENSG00000197576 | HXA4_HUMAN | 7 | 27135369 | 27136877 | 27136392 | -1 | 2 | 320 | 627.91 |
p8 | HOXA5 | ENSP00000222726 | ENST00000222726 | ENSG00000106004 | HXA5_HUMAN | 7 | 27147979 | 27149751 | 27149341 | -1 | 2 | 270 | 517.03 |
p9 | HOXA6 | ENSP00000222728 | ENST00000222728 | ENSG00000106006 | HXA6_HUMAN | 7 | 27151802 | 27153893 | 27153537 | -1 | 2 | 233 | 460.35 |
p10 | HOXA7 | ENSP00000242159 | ENST00000242159 | ENSG00000122592 | HXA7_HUMAN | 7 | 27161053 | 27162689 | 27162339 | -1 | 2 | 230 | 444.86 |
p11 | HOXA9 | ENSP00000343619 | ENST00000343483 | ENSG00000078399 | HXA9_HUMAN | 7 | 27169747 | 27171601 | 27171188 | -1 | 2 | 272 | 528.64 |
p12 | HOXA10 | ENSP00000283921 | ENST00000283921 | ENSG00000153807 | HXA10_HUMAN | 7 | 27178043 | 27180399 | 27179803 | -1 | 2 | 393 | 663.81 |
p13 | HOXA11 | ENSP00000006015 | ENST00000006015 | ENSG00000005073 | HXA11_HUMAN | 7 | 27188940 | 27191288 | 27190812 | -1 | 2 | 313 | 377.85 |
p14 | HOXA13 | ENSP00000222753 | ENST00000222753 | ENSG00000106031 | HXA13_HUMAN | 7 | 27204342 | 27206221 | 27205634 | -1 | 2 | 388 | 607.14 |
p15 | EVX1 | ENSP00000222761 | ENST00000222761 | ENSG00000106038 | EVX1_HUMAN | 7 | 27249175 | 27252569 | 27251371 | 1 | 3 | 407 | 588.83 |
p16 | A4D198_HUMAN | ENSP00000322111 | ENST00000313812 | ENSG00000177093 | A4D198_HUMAN | 7 | 27464307 | 27464999 | 27464649 | -1 | 1 | 230 | 433.46 |
p17 | HIBADH | ENSP00000265395 | ENST00000265395 | ENSG00000106049 | 3HIDH_HUMAN | 7 | 27532358 | 27668932 | 27549219 | -1 | 8 | 336 | 654.39 |
Parameter used for the loci-alignments
qLoci-Score_CutOff: 100 bitsqLoci-MaxProtOverlap: 40 aa
loci size factor: 2 (additional loci size constraint: 0 nt)
loci-grouping type: loci intervalls
max distance between non-highlighted (orange) target columns: 500000 nt
RelativeScore color index:
<= 33 | <= 66 | <= 100 | <= 133 | <= 166 | <= 200 | <= 233 | <= 266 | <= 300 | <= 333 | <= 366 | <= 400 | <= 433 | <= 466 | <= 500 | <= 533 | <= 566 | <= 600 | <= 633 | <= 666 | <= 700 | <= 733 | <= 766 | <= 800 | <= 833 | <= 866 | <= 900 | <= 933 | <= 966 | <= 1000 | relSc>1000 |
<= 33 | <= 66 | <= 100 | <= 133 | <= 166 | <= 200 | <= 233 | <= 266 | <= 300 | <= 333 | <= 366 | <= 400 | <= 433 | <= 466 | <= 500 | <= 533 | <= 566 | <= 600 | <= 633 | <= 666 | <= 700 | <= 733 | <= 766 | <= 800 | <= 833 | <= 866 | <= 900 | <= 933 | <= 966 | <= 1000 | relSc>1000 |
region 1
retrieve target region: getEnsemblProteins.pl -h Danio_rerio -l 16 -i 15878347:17844753 -f 15e5 some_geneID_to_be_selected
scoreRatio_sum=13.08 log_scoreRatio_sum=3.29 focal_scoreRatio_sum=3.66
AlnScore=4073 (based on relative scores)
AlnType: normal (increasing chromosome positions)
QueryProtein(s)=ENSP00000343619 (contained in p11)
TargetGenome=Danio_rerio
ref-loci | target-loci | aln | protID | geneName | optQloci | target-loci | score | chr | startPos | endPos | ori | hits | queryCov | meanIdentity | hitsLength | intra_inter | compara | globalRank |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
p1 | q1 | +/+ | ENSP00000005587 | SKAP2 | q1 | q1 | 385.44 | 16 | 15905869 | 15946733 | -1 | 8 | 69.9% | 66% | 804 | 0.59 / 0.48 = 1.23 | ortholog_one2one: skap2 | 1 |
p2 | --- | gapq | ENSP00000328286 | - | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p3 | --- | gapq | ENSP00000343246 | HOXA1 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p4 | q2 | +/+ | ENSP00000222718 | HOXA2 | q2 | q2 | 473.02 | 16 | 15953161 | 15954846 | -1 | 2 | 98.9% | 71% | 1071 | 0.55 / 0.3 = 1.83 | ortholog_one2one: hoxa2b | 1 |
p5 | --- | gapq | ENSP00000324884 | HOXA3 | q2 | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p6 | --- | gapq | ENSP00000297027 | Q96MZ3_HUMAN | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p7 | --- | gapq | ENSP00000353151 | HOXA4 | q2 | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p8 | --- | gapq | ENSP00000222726 | HOXA5 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p9 | --- | gapq | ENSP00000222728 | HOXA6 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p10 | --- | gapq | ENSP00000242159 | HOXA7 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p11 | q3 | +/+ | ENSP00000343619 | HOXA9 | q3 | q3 | 226.96 | 16 | 15965005 | 15966531 | -1 | 2 | 99.6% | 48.9% | 774 | 0.55 / 0.57 = 0.96 | noComparaHits: hoxa9b | 3 |
p12 | q4 | +/+ | ENSP00000283921 | HOXA10 | q4 | q4 | 237.87 | 16 | 15969590 | 15971748 | -1 | 2 | 65.4% | 56% | 696 | 0.65 / 0.64 = 1.02 | noComparaHits: hoxa10b | 1 |
p13 | q5 | +/+ | ENSP00000006015 | HOXA11 | q5 | q5 | 344.19 | 16 | 15975493 | 15977085 | -1 | 2 | 87.2% | 67% | 813 | 0.25 / 0.08 = 3.13 | ortholog_one2many: hoxa11b | 1 |
p14 | q6 | +/+ | ENSP00000222753 | HOXA13 | q6 | q6 | 249.84 | 16 | 15984766 | 15985716 | -1 | 2 | 50.3% | 66.5% | 579 | 0.58 / 0.58 = 1 | ortholog_one2many: hoxa13b | 3 |
p15 | --- | gapq | ENSP00000222761 | EVX1 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p16 | --- | gapq | ENSP00000322111 | A4D198_HUMAN | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p17 | q7 | +/+ | ENSP00000265395 | HIBADH | q7 | q7 | 507.48 | 16 | 15993005 | 16007851 | -1 | 7 | 90.5% | 82% | 933 | 0.86 / 0.22 = 3.91 | ortholog_one2many: hibadh | 1 |
region 2
retrieve target region: getEnsemblProteins.pl -h Danio_rerio -l 19 -i 8631227:10562315 -f 14e5 some_geneID_to_be_selected
scoreRatio_sum=14.73 log_scoreRatio_sum=2.58 focal_scoreRatio_sum=3.63
AlnScore=5581 (based on relative scores)
AlnType: reversed (decreasing chromosome positions)
QueryProtein(s)=ENSP00000343619 (contained in p11)
TargetGenome=Danio_rerio
ref-loci | target-loci | aln | protID | geneName | optQloci | target-loci | score | chr | startPos | endPos | ori | hits | queryCov | meanIdentity | hitsLength | intra_inter | compara | globalRank |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
p1 | --- | gaps | ENSP00000005587 | SKAP2 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p2 | --- | gaps | ENSP00000328286 | - | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p3 | q1 | +/+ | ENSP00000343246 | HOXA1 | q1 | q1 | 328.34 | 19 | 10547332 | 10548513 | 1 | 2 | 98.2% | 56% | 993 | 0.69 / 0.46 = 1.5 | ortholog_one2one: hoxa1a | 1 |
p4 | q2 | +/+ | ENSP00000222718 | HOXA2 | q2 | q2 | 133.33 | 19 | 10543546 | 10544525 | 1 | 2 | 49.2% | 48.9% | 510 | 0.55 / 0.8 = 0.69 | noComparaHits: | 3 |
p5 | q3 | +/+ | ENSP00000324884 | HOXA3 | q3 | q3 | 391.01 | 19 | 10538806 | 10540642 | 1 | 2 | 87.6% | 57.9% | 1149 | 0.26 / 0.25 = 1.04 | ortholog_one2one: hoxa3a | 2 |
p6 | --- | gapq | ENSP00000297027 | Q96MZ3_HUMAN | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p7 | q4 | +/+ | ENSP00000353151 | HOXA4 | q4 | q4 | 191.4 | 19 | 10528761 | 10529933 | 1 | 2 | 74.4% | 47.1% | 723 | 0.59 / 0.69 = 0.86 | ortholog_one2one: hoxa4a | 2 |
p8 | q5 | +/+ | ENSP00000222726 | HOXA5 | q5 | q5 | 331.87 | 19 | 10520701 | 10522002 | 1 | 2 | 100% | 66.5% | 825 | 0.41 / 0.35 = 1.17 | ortholog_one2one: hoxa5a | 1 |
p9 | --- | gapq | ENSP00000222728 | HOXA6 | q4 | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p10 | --- | gapq | ENSP00000242159 | HOXA7 | q5 | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p11 | q6 | +/+ | ENSP00000343619 | HOXA9 | q6 | q6 | 181.55 | 19 | 10511297 | 10512339 | 1 | 2 | 63.2% | 58% | 501 | 0.55 / 0.65 = 0.85 | noComparaHits: hoxa9a | 5 |
p12 | --- | gapq | ENSP00000283921 | HOXA10 | q6 | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p13 | q7 | +/+ | ENSP00000006015 | HOXA11 | q7 | q7 | 337.14 | 19 | 10498422 | 10499983 | 1 | 2 | 91.7% | 62.6% | 858 | 0.25 / 0.1 = 2.5 | ortholog_one2many: hoxa11a | 2 |
p14 | q8 | +/+ | ENSP00000222753 | HOXA13 | q8 | q8 | 295.26 | 19 | 10490838 | 10491773 | 1 | 2 | 71.4% | 60.2% | 813 | 0.58 / 0.51 = 1.14 | ortholog_one2many: hoxa13a | 1 |
p15 | q9 | +/+ | ENSP00000222761 | EVX1 | q9 | q9 | 411.55 | 19 | 10480188 | 10482503 | -1 | 3 | 95.3% | 59.7% | 1107 | 0.42 / 0.3 = 1.4 | ortholog_one2one: evx1 | 1 |
p16 | --- | gapq | ENSP00000322111 | A4D198_HUMAN | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p17 | q10 | +/+ | ENSP00000265395 | HIBADH | q10 | q10 | 494.44 | 19 | 10363653 | 10418066 | 1 | 7 | 89.3% | 72.9% | 1047 | 0.86 / 0.24 = 3.58 | ortholog_one2many: zgc:100804 | 2 |
region 3
retrieve target region: getEnsemblProteins.pl -h Danio_rerio -l 12 -i 26131306:28039019 -f 14e5 some_geneID_to_be_selected
scoreRatio_sum=4.66 log_scoreRatio_sum=-0.39 focal_scoreRatio_sum=1.12
AlnScore=2119 (based on relative scores)
AlnType: normal (increasing chromosome positions)
QueryProtein(s)=ENSP00000343619 (contained in p11)
TargetGenome=Danio_rerio
ref-loci | target-loci | aln | protID | geneName | optQloci | target-loci | score | chr | startPos | endPos | ori | hits | queryCov | meanIdentity | hitsLength | intra_inter | compara | globalRank |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
p1 | q1 | +/+ | ENSP00000005587 | SKAP2 | q1 | q1 | 327.37 | 12 | 26394051 | 26440888 | -1 | 8 | 77.7% | 49.8% | 945 | 0.59 / 0.56 = 1.05 | between_species_paralog: skap2 | 2 |
p2 | --- | gapq | ENSP00000328286 | - | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p3 | q2 | +/+ | ENSP00000343246 | HOXA1 | q2 | q2 | 183.66 | 12 | 26456223 | 26457244 | -1 | 2 | 97.9% | 39.8% | 939 | 0.69 / 0.7 = 0.99 | noComparaHits: hoxb1b | 3 |
p4 | --- | gapq | ENSP00000222718 | HOXA2 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p5 | --- | gapq | ENSP00000324884 | HOXA3 | q3 | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p6 | --- | gapq | ENSP00000297027 | Q96MZ3_HUMAN | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p7 | --- | gapq | ENSP00000353151 | HOXA4 | q3 | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p8 | q3 | +/+ | ENSP00000222726 | HOXA5 | q3 | q3 | 285.4 | 12 | 26467712 | 26468987 | -1 | 2 | 98.1% | 57.7% | 816 | 0.41 / 0.44 = 0.93 | between_species_paralog: hoxb5b | 3 |
p9 | q4 | +/+ | ENSP00000222728 | HOXA6 | q4 | q4 | 232.94 | 12 | 26470452 | 26471559 | -1 | 2 | 99.6% | 58.1% | 675 | 0.48 / 0.49 = 0.98 | ortholog_one2one: hoxb6b | 2 |
p10 | q5 | +/+ | ENSP00000242159 | HOXA7 | q5 | q5 | 149.51 | 12 | 26478803 | 26480924 | -1 | 2 | 85.7% | 46.8% | 642 | 0.47 / 0.66 = 0.71 | noComparaHits: hoxb8b | 3 |
p11 | --- | gape | ENSP00000343619 | HOXA9 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p12 | --- | gape | ENSP00000283921 | HOXA10 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p13 | --- | gape | ENSP00000006015 | HOXA11 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p14 | --- | gape | ENSP00000222753 | HOXA13 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p15 | --- | gape | ENSP00000222761 | EVX1 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p16 | --- | gape | ENSP00000322111 | A4D198_HUMAN | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p17 | --- | gape | ENSP00000265395 | HIBADH | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
region 4
retrieve target region: getEnsemblProteins.pl -h Danio_rerio -l 11 -i 4109:1929754 -f 14e5 some_geneID_to_be_selected
scoreRatio_sum=2.62 log_scoreRatio_sum=-0.4 focal_scoreRatio_sum=0.79
AlnScore=1490 (based on relative scores)
AlnType: reversed (decreasing chromosome positions)
QueryProtein(s)=ENSP00000343619 (contained in p11)
TargetGenome=Danio_rerio
ref-loci | target-loci | aln | protID | geneName | optQloci | target-loci | score | chr | startPos | endPos | ori | hits | queryCov | meanIdentity | hitsLength | intra_inter | compara | globalRank |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
p1 | --- | gaps | ENSP00000005587 | SKAP2 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p2 | --- | gaps | ENSP00000328286 | - | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p3 | --- | gaps | ENSP00000343246 | HOXA1 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p4 | --- | gaps | ENSP00000222718 | HOXA2 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p5 | --- | gaps | ENSP00000324884 | HOXA3 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p6 | --- | gaps | ENSP00000297027 | Q96MZ3_HUMAN | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p7 | --- | gaps | ENSP00000353151 | HOXA4 | q1 | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p8 | --- | gaps | ENSP00000222726 | HOXA5 | q1 | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p9 | q1 | +/+ | ENSP00000222728 | HOXA6 | q1 | q1 | 194.92 | 11 | 589745 | 590834 | 1 | 2 | 100% | 47% | 684 | 0.48 / 0.57 = 0.84 | noComparaHits: hoxc6b | 4 |
p10 | --- | gapq | ENSP00000242159 | HOXA7 | q1 | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p11 | --- | gapq | ENSP00000343619 | HOXA9 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p12 | --- | gapq | ENSP00000283921 | HOXA10 | q2 | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p13 | q2 | +/+ | ENSP00000006015 | HOXA11 | q2 | q2 | 260.75 | 11 | 566842 | 568428 | 1 | 2 | 93.3% | 51.2% | 852 | 0.25 / 0.3 = 0.83 | noComparaHits: hoxc11b | 5 |
p14 | q3 | +/+ | ENSP00000222753 | HOXA13 | q3 | q3 | 232.94 | 11 | 547516 | 549822 | 1 | 2 | 58.5% | 59.1% | 642 | 0.58 / 0.61 = 0.95 | noComparaHits: hoxc13b | 5 |
p15 | --- | gape | ENSP00000222761 | EVX1 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p16 | --- | gape | ENSP00000322111 | A4D198_HUMAN | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p17 | --- | gape | ENSP00000265395 | HIBADH | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
region 5
retrieve target region: getEnsemblProteins.pl -h Danio_rerio -l 23 -i 40370623:42333822 -f 15e5 some_geneID_to_be_selected
scoreRatio_sum=0.48 log_scoreRatio_sum=-0.72 focal_scoreRatio_sum=0.05
AlnScore=596 (based on relative scores)
AlnType: reversed (decreasing chromosome positions)
QueryProtein(s)=ENSP00000343619 (contained in p11)
TargetGenome=Danio_rerio
ref-loci | target-loci | aln | protID | geneName | optQloci | target-loci | score | chr | startPos | endPos | ori | hits | queryCov | meanIdentity | hitsLength | intra_inter | compara | globalRank |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
p1 | --- | gaps | ENSP00000005587 | SKAP2 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p2 | q1 | +/+ | ENSP00000328286 | - | q1 | q1 | 201.04 | 23 | 42161159 | 42162169 | 1 | 3 | 75.8% | 58.1% | 480 | 0.19 / 0.4 = 0.48 | between_species_paralog: HMGB2 (2 of 3) | 3 |
p3 | --- | gape | ENSP00000343246 | HOXA1 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p4 | --- | gape | ENSP00000222718 | HOXA2 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p5 | --- | gape | ENSP00000324884 | HOXA3 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p6 | --- | gape | ENSP00000297027 | Q96MZ3_HUMAN | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p7 | --- | gape | ENSP00000353151 | HOXA4 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p8 | --- | gape | ENSP00000222726 | HOXA5 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p9 | --- | gape | ENSP00000222728 | HOXA6 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p10 | --- | gape | ENSP00000242159 | HOXA7 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p11 | --- | gape | ENSP00000343619 | HOXA9 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p12 | --- | gape | ENSP00000283921 | HOXA10 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p13 | --- | gape | ENSP00000006015 | HOXA11 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p14 | --- | gape | ENSP00000222753 | HOXA13 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p15 | --- | gape | ENSP00000222761 | EVX1 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p16 | --- | gape | ENSP00000322111 | A4D198_HUMAN | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p17 | --- | gape | ENSP00000265395 | HIBADH | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
region 6
retrieve target region: getEnsemblProteins.pl -h Danio_rerio -l 9 -i 1921957:3874634 -f 15e5 some_geneID_to_be_selected
scoreRatio_sum=6.38 log_scoreRatio_sum=-0.74 focal_scoreRatio_sum=2.52
AlnScore=3269 (based on relative scores)
AlnType: normal (increasing chromosome positions)
QueryProtein(s)=ENSP00000343619 (contained in p11)
TargetGenome=Danio_rerio
ref-loci | target-loci | aln | protID | geneName | optQloci | target-loci | score | chr | startPos | endPos | ori | hits | queryCov | meanIdentity | hitsLength | intra_inter | compara | globalRank |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
p1 | --- | gaps | ENSP00000005587 | SKAP2 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p2 | --- | gaps | ENSP00000328286 | - | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p3 | --- | gaps | ENSP00000343246 | HOXA1 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p4 | --- | gaps | ENSP00000222718 | HOXA2 | q1 | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p5 | q1 | +/+ | ENSP00000324884 | HOXA3 | q1 | q1 | 305.81 | 9 | 1922029 | 1923358 | -1 | 2 | 84.4% | 49.3% | 1047 | 0.26 / 0.41 = 0.63 | between_species_paralog: hoxd3a | 3 |
p6 | --- | gapq | ENSP00000297027 | Q96MZ3_HUMAN | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p7 | q2 | +/+ | ENSP00000353151 | HOXA4 | q2 | q2 | 189.64 | 9 | 1933897 | 1934984 | -1 | 2 | 45.9% | 67.8% | 429 | 0.59 / 0.69 = 0.86 | between_species_paralog: hoxd4a | 4 |
p8 | --- | gapq | ENSP00000222726 | HOXA5 | q2 | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p9 | --- | gapq | ENSP00000222728 | HOXA6 | q2 | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p10 | --- | gapq | ENSP00000242159 | HOXA7 | q2 | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p11 | q3 | +/+ | ENSP00000343619 | HOXA9 | q3 | q3 | 239.99 | 9 | 1948806 | 1949904 | -1 | 2 | 99.6% | 48% | 855 | 0.55 / 0.54 = 1.02 | noComparaHits: hoxd9a | 1 |
p12 | q4 | +/+ | ENSP00000283921 | HOXA10 | q4 | q4 | 208.66 | 9 | 1952491 | 1953931 | -1 | 2 | 42% | 68.7% | 480 | 0.65 / 0.68 = 0.96 | noComparaHits: hoxd10a | 2 |
p13 | q5 | +/+ | ENSP00000006015 | HOXA11 | q5 | q5 | 284.69 | 9 | 1960574 | 1962255 | -1 | 2 | 91.1% | 56.1% | 825 | 0.25 / 0.24 = 1.04 | noComparaHits: hoxd11a | 4 |
p14 | q6 | +/+ | ENSP00000222753 | HOXA13 | q6 | q6 | 161.13 | 9 | 1971944 | 1974397 | -1 | 2 | 57.7% | 46.5% | 651 | 0.58 / 0.73 = 0.79 | noComparaHits: hoxd13a | 6 |
p15 | q7 | +/+ | ENSP00000222761 | EVX1 | q7 | q7 | 358.87 | 9 | 1987346 | 1989676 | 1 | 4 | 74.2% | 63.1% | 918 | 0.42 / 0.39 = 1.08 | between_species_paralog: evx2 | 2 |
p16 | --- | gape | ENSP00000322111 | A4D198_HUMAN | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p17 | --- | gape | ENSP00000265395 | HIBADH | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
region 7
retrieve target region: getEnsemblProteins.pl -h Danio_rerio -l 3 -i 21211959:23186838 -f 15e5 some_geneID_to_be_selected
scoreRatio_sum=10.53 log_scoreRatio_sum=-0.76 focal_scoreRatio_sum=3.29
AlnScore=4690 (based on relative scores)
AlnType: reversed (decreasing chromosome positions)
QueryProtein(s)=ENSP00000343619 (contained in p11)
TargetGenome=Danio_rerio
ref-loci | target-loci | aln | protID | geneName | optQloci | target-loci | score | chr | startPos | endPos | ori | hits | queryCov | meanIdentity | hitsLength | intra_inter | compara | globalRank |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
p1 | --- | gaps | ENSP00000005587 | SKAP2 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p2 | --- | gaps | ENSP00000328286 | - | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p3 | q1 | +/+ | ENSP00000343246 | HOXA1 | q1 | q1 | 217.46 | 3 | 23124590 | 23126293 | 1 | 2 | 99.1% | 45.1% | 969 | 0.69 / 0.64 = 1.08 | noComparaHits: hoxb1a | 2 |
p4 | q2 | +/+ | ENSP00000222718 | HOXA2 | q2 | q2 | 299.12 | 3 | 23107926 | 23109945 | 1 | 2 | 99.5% | 50.9% | 1146 | 0.55 / 0.55 = 1 | between_species_paralog: hoxb2a | 2 |
p5 | q3 | +/+ | ENSP00000324884 | HOXA3 | q3 | q3 | 427.97 | 3 | 23101788 | 23103710 | 1 | 2 | 100% | 56.2% | 1245 | 0.26 / 0.18 = 1.44 | between_species_paralog: hoxb3a | 1 |
p6 | --- | gapq | ENSP00000297027 | Q96MZ3_HUMAN | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p7 | q4 | +/+ | ENSP00000353151 | HOXA4 | q4 | q4 | 206.55 | 3 | 23077620 | 23079309 | 1 | 2 | 71.9% | 51.9% | 678 | 0.59 / 0.67 = 0.88 | between_species_paralog: hoxb4a | 1 |
p8 | q5 | +/+ | ENSP00000222726 | HOXA5 | q5 | q5 | 291.03 | 3 | 23063599 | 23065038 | 1 | 2 | 100% | 58.8% | 858 | 0.41 / 0.43 = 0.95 | between_species_paralog: hoxb5a | 2 |
p9 | q6 | +/+ | ENSP00000222728 | HOXA6 | q6 | q6 | 250.55 | 3 | 23059516 | 23061253 | 1 | 2 | 99.1% | 59.1% | 681 | 0.48 / 0.45 = 1.07 | between_species_paralog: hoxb6a | 1 |
--- | q7 | gapp | - | - | - | q7 | - | - | - | - | - | - | - | - | - | - | - | - |
p10 | q8 | +/+ | ENSP00000242159 | HOXA7 | q8 | q8 | 141.78 | 3 | 23044103 | 23045506 | 1 | 2 | 86.5% | 44.1% | 654 | 0.47 / 0.68 = 0.69 | noComparaHits: hoxb8a | 4 |
p11 | q9 | +/+ | ENSP00000343619 | HOXA9 | q9 | q9 | 212.88 | 3 | 23033313 | 23036568 | 1 | 2 | 82.7% | 54.2% | 621 | 0.55 / 0.59 = 0.93 | noComparaHits: hoxb9a | 4 |
p12 | q10 | +/+ | ENSP00000283921 | HOXA10 | q10 | q10 | 131.43 | 3 | 23026693 | 23026944 | 1 | 1 | 21.1% | 82.1% | 252 | 0.65 / 0.8 = 0.81 | noComparaHits: hoxb10a | 5 |
p13 | --- | gapq | ENSP00000006015 | HOXA11 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p14 | q11 | +/+ | ENSP00000222753 | HOXA13 | q11 | q11 | 280.82 | 3 | 23010358 | 23011476 | 1 | 2 | 62.9% | 63.4% | 690 | 0.58 / 0.53 = 1.09 | between_species_paralog: hoxb13a | 2 |
p15 | q12 | +/+ | ENSP00000222761 | EVX1 | q12 | q12 | 167.47 | 3 | 22998210 | 22999095 | -1 | 2 | 45.7% | 51.1% | 537 | 0.42 / 0.71 = 0.59 | noComparaHits: eve1 | 3 |
p16 | --- | gape | ENSP00000322111 | A4D198_HUMAN | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p17 | --- | gape | ENSP00000265395 | HIBADH | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
region 8
retrieve target region: getEnsemblProteins.pl -h Danio_rerio -l 24 -i 19763797:21724407 -f 15e5 some_geneID_to_be_selected
scoreRatio_sum=0.33 log_scoreRatio_sum=-1.1 focal_scoreRatio_sum=0.05
AlnScore=204 (based on relative scores)
AlnType: reversed (decreasing chromosome positions)
QueryProtein(s)=ENSP00000343619 (contained in p11)
TargetGenome=Danio_rerio
ref-loci | target-loci | aln | protID | geneName | optQloci | target-loci | score | chr | startPos | endPos | ori | hits | queryCov | meanIdentity | hitsLength | intra_inter | compara | globalRank |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
p1 | --- | gaps | ENSP00000005587 | SKAP2 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p2 | --- | gaps | ENSP00000328286 | - | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p3 | --- | gaps | ENSP00000343246 | HOXA1 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p4 | --- | gaps | ENSP00000222718 | HOXA2 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p5 | q1 | +/+ | ENSP00000324884 | HOXA3 | q1 | q1 | 107.28 | 24 | 20272372 | 20274036 | 1 | 2 | 16% | 70.4% | 213 | 0.26 / 0.79 = 0.33 | noComparaHits: pdx1 | 9 |
p6 | --- | gape | ENSP00000297027 | Q96MZ3_HUMAN | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p7 | --- | gape | ENSP00000353151 | HOXA4 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p8 | --- | gape | ENSP00000222726 | HOXA5 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p9 | --- | gape | ENSP00000222728 | HOXA6 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p10 | --- | gape | ENSP00000242159 | HOXA7 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p11 | --- | gape | ENSP00000343619 | HOXA9 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p12 | --- | gape | ENSP00000283921 | HOXA10 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p13 | --- | gape | ENSP00000006015 | HOXA11 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p14 | --- | gape | ENSP00000222753 | HOXA13 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p15 | --- | gape | ENSP00000222761 | EVX1 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p16 | --- | gape | ENSP00000322111 | A4D198_HUMAN | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p17 | --- | gape | ENSP00000265395 | HIBADH | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
region 9
retrieve target region: getEnsemblProteins.pl -h Danio_rerio -l 23 -i 31855395:33831080 -f 15e5 some_geneID_to_be_selected
scoreRatio_sum=7.54 log_scoreRatio_sum=-1.98 focal_scoreRatio_sum=3.02
AlnScore=3322 (based on relative scores)
AlnType: reversed (decreasing chromosome positions)
QueryProtein(s)=ENSP00000343619 (contained in p11)
TargetGenome=Danio_rerio
ref-loci | target-loci | aln | protID | geneName | optQloci | target-loci | score | chr | startPos | endPos | ori | hits | queryCov | meanIdentity | hitsLength | intra_inter | compara | globalRank |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
p1 | --- | gaps | ENSP00000005587 | SKAP2 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p2 | --- | gaps | ENSP00000328286 | - | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p3 | q1 | +/+ | ENSP00000343246 | HOXA1 | q3 | q1 | 102.22 | 23 | 33830835 | 33831080 | 1 | 1 | 24.8% | 71.1% | 246 | 0.69 / 0.83 = 0.83 | noComparaHits: hoxc1a | 5 |
p4 | --- | gapq | ENSP00000222718 | HOXA2 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p5 | q2 | +/+ | ENSP00000324884 | HOXA3 | q2 | q2 | 101.16 | 23 | 33795334 | 33795546 | 1 | 1 | 16% | 74.6% | 213 | 0.26 / 0.8 = 0.33 | noComparaHits: hoxc3a | 10 |
p6 | --- | gapq | ENSP00000297027 | Q96MZ3_HUMAN | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p7 | q3 | +/+ | ENSP00000353151 | HOXA4 | q3 | q3 | 190.35 | 23 | 33778862 | 33779867 | 1 | 2 | 55% | 61.6% | 483 | 0.59 / 0.69 = 0.86 | between_species_paralog: hoxc4a | 3 |
p8 | --- | gapq | ENSP00000222726 | HOXA5 | q4 | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p9 | q4 | +/+ | ENSP00000222728 | HOXA6 | q4 | q4 | 206.67 | 23 | 33763064 | 33767828 | 1 | 3 | 92.7% | 49.4% | 654 | 0.48 / 0.55 = 0.87 | noComparaHits: hoxc6a
; hoxc5a |
3 |
p10 | q5 | +/+ | ENSP00000242159 | HOXA7 | q5 | q5 | 151.27 | 23 | 33749042 | 33751044 | 1 | 2 | 80% | 50.8% | 534 | 0.47 / 0.65 = 0.72 | noComparaHits: hoxc8a | 2 |
p11 | q6 | +/+ | ENSP00000343619 | HOXA9 | q6 | q6 | 238.58 | 23 | 33742961 | 33744781 | 1 | 2 | 98.5% | 49.6% | 765 | 0.55 / 0.54 = 1.02 | noComparaHits: hoxc9a | 2 |
p12 | q7 | +/+ | ENSP00000283921 | HOXA10 | q7 | q7 | 182.6 | 23 | 33731209 | 33733955 | 1 | 2 | 64.9% | 46.4% | 729 | 0.65 / 0.72 = 0.9 | noComparaHits: hoxc10a | 3 |
p13 | q8 | +/+ | ENSP00000006015 | HOXA11 | q8 | q8 | 285.05 | 23 | 33722561 | 33724786 | 1 | 2 | 93.3% | 55.5% | 852 | 0.25 / 0.24 = 1.04 | noComparaHits: hoxc11a | 3 |
p14 | q9 | +/+ | ENSP00000222753 | HOXA13 | q9 | q9 | 242.45 | 23 | 33701748 | 33704206 | 1 | 2 | 62.1% | 58.8% | 678 | 0.58 / 0.6 = 0.97 | noComparaHits: hoxc13a | 4 |
p15 | --- | gape | ENSP00000222761 | EVX1 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p16 | --- | gape | ENSP00000322111 | A4D198_HUMAN | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p17 | --- | gape | ENSP00000265395 | HIBADH | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
region 10
retrieve target region: getEnsemblProteins.pl -h Danio_rerio -l 23 -i 35047023:37012084 -f 15e5 some_geneID_to_be_selected
scoreRatio_sum=7.54 log_scoreRatio_sum=-1.98 focal_scoreRatio_sum=3.02
AlnScore=3318 (based on relative scores)
AlnType: normal (increasing chromosome positions)
QueryProtein(s)=ENSP00000343619 (contained in p11)
TargetGenome=Danio_rerio
ref-loci | target-loci | aln | protID | geneName | optQloci | target-loci | score | chr | startPos | endPos | ori | hits | queryCov | meanIdentity | hitsLength | intra_inter | compara | globalRank |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
--- | q1 | gaps | - | - | - | q1 | - | - | - | - | - | - | - | - | - | - | - | - |
p1 | --- | gapq | ENSP00000005587 | SKAP2 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p2 | --- | gapq | ENSP00000328286 | - | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p3 | q2 | +/+ | ENSP00000343246 | HOXA1 | q4 | q2 | 102.22 | 23 | 35159197 | 35159442 | -1 | 1 | 24.8% | 71.1% | 246 | 0.69 / 0.83 = 0.83 | noComparaHits: hoxc1a | 5 |
p4 | --- | gapq | ENSP00000222718 | HOXA2 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p5 | q3 | +/+ | ENSP00000324884 | HOXA3 | q5 | q3 | 101.16 | 23 | 35194845 | 35195057 | -1 | 1 | 16% | 74.6% | 213 | 0.26 / 0.8 = 0.33 | noComparaHits: hoxc3a | 10 |
p6 | --- | gapq | ENSP00000297027 | Q96MZ3_HUMAN | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p7 | q4 | +/+ | ENSP00000353151 | HOXA4 | q4 | q4 | 190.35 | 23 | 35210616 | 35211621 | -1 | 2 | 55% | 61.6% | 483 | 0.59 / 0.69 = 0.86 | between_species_paralog: hoxc4a | 3 |
p8 | --- | gapq | ENSP00000222726 | HOXA5 | q5 | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p9 | q5 | +/+ | ENSP00000222728 | HOXA6 | q5 | q5 | 206.67 | 23 | 35222647 | 35227411 | -1 | 3 | 92.7% | 49.4% | 654 | 0.48 / 0.55 = 0.87 | noComparaHits: hoxc5a
; hoxc6a |
3 |
p10 | q6 | +/+ | ENSP00000242159 | HOXA7 | q6 | q6 | 151.27 | 23 | 35239388 | 35241390 | -1 | 2 | 80% | 50.8% | 534 | 0.47 / 0.65 = 0.72 | noComparaHits: hoxc8a | 2 |
p11 | q7 | +/+ | ENSP00000343619 | HOXA9 | q7 | q7 | 238.58 | 23 | 35245651 | 35247471 | -1 | 2 | 98.5% | 49.6% | 765 | 0.55 / 0.54 = 1.02 | noComparaHits: hoxc9a | 2 |
p12 | q8 | +/+ | ENSP00000283921 | HOXA10 | q8 | q8 | 182.6 | 23 | 35256479 | 35259225 | -1 | 2 | 64.9% | 46.4% | 729 | 0.65 / 0.72 = 0.9 | noComparaHits: hoxc10a | 3 |
p13 | q9 | +/+ | ENSP00000006015 | HOXA11 | q9 | q9 | 285.05 | 23 | 35265648 | 35267873 | -1 | 2 | 93.3% | 55.5% | 852 | 0.25 / 0.24 = 1.04 | noComparaHits: hoxc11a | 3 |
p14 | q10 | +/+ | ENSP00000222753 | HOXA13 | q10 | q10 | 242.45 | 23 | 35287160 | 35289618 | -1 | 2 | 62.1% | 58.8% | 678 | 0.58 / 0.6 = 0.97 | noComparaHits: hoxc13a | 4 |
p15 | --- | gape | ENSP00000222761 | EVX1 | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p16 | --- | gape | ENSP00000322111 | A4D198_HUMAN | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |
p17 | --- | gape | ENSP00000265395 | HIBADH | noMatch | --- | - | - | - | - | - | - | - | - | - | - | - | - |