S1: Conservation of Interactions with Known Modifications

1. Methylations in 18S rRNA: [jpg] [eps]
2. Pseudouridylations in 18S rRNA: [jpg] [eps]
3. Methylations in 28S rRNA: [jpg] [eps]
4. Pseudouridylations in 28S rRNA: [jpg] [eps]
5. Pseudouridylations and Methylations in 5.8S rRNA: [jpg] [eps]
6. Pseudouridylations and Methylations in snRNAs: [jpg] [eps]

S2: Expression of Hostgenes of Redundant SnoRNA Guides

1. Table with Hostgene Expression [html] [csv]

S3: SnoRNA Family Alignments and Their Interactions

1. Table with box H/ACA snoRNAs [html] [csv] [xls]
2. Table with box C/D snoRNAs [html] [csv] [xls]

S4: Predictions for Orphan Modifications and Orphan SnoRNAs

1. Predictions for orphan modifications
1. Table [html], [csv]
2. Conservation of putative Interactions with 18S rRNA [jpg] [eps]
3. Conservation of putative Interactions with 28S rRNA [jpg] [eps]
4. Conservation of putative Interactions with U2 snRNA [jpg] [eps]
2. Predictions for orphan snoRNAs
   1. Table [html], [csv]
   2. Conservation of putative Interactions with 18S rRNA [jpg] [eps]
   3. Conservation of putative Interactions with 28S rRNA [jpg] [eps]

S5: Pylogenetic Tree of vertebrates

1. Pylogenetic tree of 47 investigated vertebrates: [jpg] [eps]

S6: RNAsalsa alignments of ribosomal RNAs

1. vertebrate 18S rRNA alignment: [aln]
2. vertebrate 28S rRNA alignment: [aln]
3. vertebrate 5.8S rRNA alignment: [aln]
4. mapping between alignment columns and human modified positions: [html] [csv]

S7: Parameters used for target prediction programs

1. parameters: [html]