LOCUS       NC_007789              16254 bp    DNA     circular INV 04-APR-2006
DEFINITION  Acanthaster brevispinus mitochondrion, complete genome.
ACCESSION   NC_007789
VERSION     NC_007789.1  GI:86990375
KEYWORDS    .
SOURCE      mitochondrion Acanthaster brevispinus (starfish)
  ORGANISM  Acanthaster brevispinus
            Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Asterozoa;
            Asteroidea; Valvatacea; Valvatida; Acanthasteridae; Acanthaster.
REFERENCE   1  (bases 1 to 16254)
  AUTHORS   Yasuda,N., Hamaguchi,M., Sasaki,M., Nagai,S., Saba,M. and
            Nadaoka,K.
  TITLE     Complete mitochondrial genome sequences for Crown-of-thorns
            starfish Acanthaster planci and Acanthaster brevispinus
  JOURNAL   (er) BMC Genomics 7 (1), 17 (2006) PUBMED   16438737
REFERENCE   2  (bases 1 to 16254)
  AUTHORS   
  TITLE     Direct Submission
  JOURNAL   Submitted (08-FEB-2006) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 16254)
  AUTHORS   Yasuda,N., Hamaguchi,M., Sasaki,M. and Nadaoka,K.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2005) Tokyo Institute of Technology, Graduate
            school of Information Science and Technology; O0okayama 2-12-1,
            Meguro-ku, Tokyo 152-8552, Japan
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AB231476.
FEATURES             Location/Qualifiers
     source          1..16254
                     /mol_type="genomic DNA"
                     /db_xref="taxon:339859"
                     /organelle="mitochondrion"
                     /common="starfish"
                     /organism="Acanthaster brevispinus"
     rRNA            complement(1..1545)
                     /product="l-rRNA"
                     /note="16S ribosomal RNA"
     gene            complement(1552..2616)
                     /db_xref="GeneID:3912552"
                     /gene="ND2"
     CDS             complement(1552..2616)
                     /protein_id="YP_492666.1"
                     /gene="ND2"
                     /transl_table=9
                     /db_xref="GI:86990376"
                     /db_xref="GeneID:3912552"
                     /codon_start=1
                     /product="NADH dehydrogenase subunit 2"
                     /translation="MHRSVFIVLVVSVVFGTFVVLSSHHWFTLWVGLEVNTLSILPIL
                     CGGFLPRKVESSVKYFLVQSVSAAVILNVVVIQAWFSSSWLVGQPLLKVSSLLITLAI
                     GLKLGLFPCHYWFPDVVQGVGFLEGLVLSTWQKLAPFSVLVYVIDSVDIRVLSCLAVF
                     SVLIGGWGGLNQTQVRKILAFSSVAHMGWICSTVGYSANAGCVMLLIYIITNSSVFLI
                     ASEFDLKTLAHVGRVSYFNVGKSSGIVLGVLSLGVLPPLFGFLIKFVSLKCLLESGSV
                     LVSGFLVAGSLLSLFFYLRVSFNSSLLLFPQHSLVLFGWRGLQDGGLGVPTARGLILC
                     WGLSVSLLGLVSFPVFVSLL"
     tRNA            complement(2617..2688)
                     /product="tRNA-Ile"
     gene            complement(2688..3668)
                     /db_xref="GeneID:3912551"
                     /gene="ND1"
     CDS             complement(2688..3668)
                     /protein_id="YP_492667.1"
                     /gene="ND1"
                     /transl_table=9
                     /db_xref="GI:86990377"
                     /db_xref="GeneID:3912551"
                     /codon_start=1
                     /product="NADH dehydrogenase subunit 1"
                     /translation="MEGLVFITNSVVFIIPVLLAVALLTLVERKVLGYMQFRKGPNVV
                     GPFGLLQPIADGFKLLIKETLKPSNASPYLFFLSPILFLGIALFLWSLIPVGFCVLEV
                     NLSLVLVMGLSSLSVYALLGSGWASNSNYSFLGAVRAVAQTVSYEISLGLILLGVVVF
                     SGGFSLSVIENSQGGSWLVFCCLPLFVVWFVSTLAETNRAPFDLTEGESEIVSGYNVE
                     YAGGPFAMFFIAEYGNIIFMNLLSVVLFFGGSSPFSGVFPVGVLMVSVKTIFLVVLFL
                     WVRASYPRFRYDHLMYLTWKKYLPLSLGVLVFYSVLLVSVDILPPSLVLV"
     tRNA            complement(3669..3740)
                     /product="tRNA-Leu"
                     /note="codons recognized: UUR"
     tRNA            complement(3769..3837)
                     /product="tRNA-Gly"
                     /note="re-annotated by tRNAscan-SE"
     tRNA            complement(3839..3908)
                     /product="tRNA-Tyr"
     tRNA            3909..3979
                     /product="tRNA-Asp"
     tRNA            complement(3980..4050)
                     /product="tRNA-Met"
     tRNA            4062..4129
                     /product="tRNA-Val"
     tRNA            complement(4130..4196)
                     /product="tRNA-Cys"
     tRNA            complement(4197..4266)
                     /product="tRNA-Trp"
     tRNA            4272..4340
                     /product="tRNA-Ala"
     tRNA            complement(4341..4412)
                     /product="tRNA-Leu"
                     /note="codons recognized: CUN"
     tRNA            complement(4414..4485)
                     /product="tRNA-Asn"
     tRNA            4488..4559
                     /product="tRNA-Gln"
     tRNA            complement(4560..4629)
                     /product="tRNA-Pro"
     gene            4660..6212
                     /db_xref="GeneID:3912547"
                     /gene="COX1"
     CDS             4660..6212
                     /protein_id="YP_492668.1"
                     /gene="COX1"
                     /transl_table=9
                     /note="TAA stop codon is completed by the addition of 3'
                     A residues to the mRNA"
                     /db_xref="GI:86990378"
                     /db_xref="GeneID:3912547"
                     /codon_start=1
                     /translation="MQLSRWFFSTNHKDIGTLYLIFGAWAGMVGTAMSVIIRTELAQP
                     GSLLQDDQIYNVIVTAHALVMIFFMVMPIMIGGFGNWLIPLMIGAPDMAFPRMNNMSF
                     WLVPPSFLLLLASAGVESGAGTGWTIYPPLSSGLAHAGGSVDLAIFSLHLAGASSILA
                     SINFITTVINMRTPGISFDRLPLFVWSVFVTAFLLLLSLPVLAGAITMLLTDRNVNTT
                     FFDPAGGGDPILFQHLFWFFGHPEVYILILPGFGMISHVIAHYSGKSEPFGYLGMVYA
                     IVSIGILGFLVWAHHMFTVGMDVDTRAYFTAATMIIAVPTGIKVFSWMATLQGSNLRW
                     DTPLLWALGFVFLFTIGGLTGVILANSSIDVILHDTYYVVAHFHYVLSMGAVFAIFAG
                     FTHWFPLFSGVGLHPLWGKIHFALMFIGVNLTFFPQHFLGLAGMPRRYSDYPDAYTLW
                     NTISSIGSTISLVATLIFLFIIWEAFTSQRTTIQPEFAPSSLEWQYSSFPPSHHTFDE
                     IPATVYLIK"
                     /product="cytochrome c oxidase subunit I"
                     /transl_except=(pos:6211..6212,aa:TERM)
     tRNA            6213..6281
                     /product="tRNA-Arg"
     gene            6282..6578
                     /db_xref="GeneID:3912555"
                     /gene="ND4L"
     CDS             6282..6578
                     /protein_id="YP_492669.1"
                     /gene="ND4L"
                     /transl_table=9
                     /db_xref="GI:86990379"
                     /db_xref="GeneID:3912555"
                     /codon_start=1
                     /translation="MTPIFISTISIFYLGLLPIFFNRLHFLSILLCLELLLISLFLSI
                     TIWALNAGTNFFVANNLILLTLSACEASAGLSLMVALSRTHNLDLVIALNILQQ"
                     /product="NADH dehydrogenase subunit 4L"
                     /transl_except=(pos:6282..6284,aa:Met)
     gene            6579..7266
                     /db_xref="GeneID:3912548"
                     /gene="COX2"
     CDS             6579..7266
                     /protein_id="YP_492670.1"
                     /gene="COX2"
                     /transl_table=9
                     /note="TAA stop codon is completed by the addition of 3'
                     A residues to the mRNA"
                     /db_xref="GI:86990380"
                     /db_xref="GeneID:3912548"
                     /codon_start=1
                     /translation="MANWTQLGLQDASSPLMEELIYFHDYTLIILTLITILVFYGLAS
                     LLFSSSTNRFFLEGQGLETIWTIIPAIILIFIALPSLQLLYLMDEVNNPFLTIKAIGH
                     QWYWSYEYADYRELEFDSYMIPTSDLSSGMPRLLNVDNRLILPAQTPIRVLVSSADVL
                     HSWANLSLGVKMDAVPGRLNQVNFFISRCGIFYGQCSEICGANHSFMPIVIETTNFSS
                     FETWVSNFLTE"
                     /product="cytochrome c oxidase subunit II"
                     /transl_except=(pos:7266,aa:TERM)
     tRNA            7267..7338
                     /product="tRNA-Lys"
     gene            7340..7504
                     /db_xref="GeneID:3912546"
                     /gene="ATP8"
     CDS             7340..7504
                     /protein_id="YP_492671.1"
                     /gene="ATP8"
                     /transl_table=9
                     /db_xref="GI:86990381"
                     /db_xref="GeneID:3912546"
                     /codon_start=1
                     /product="ATP synthase F0 subunit 8"
                     /translation="MPQLNLAWWLFNFLISWATLLVVFTALLSTPPIEKPTNITTQTK
                     LHPLNNWTWN"
     gene            7489..8181
                     /db_xref="GeneID:3912558"
                     /gene="ATP6"
     CDS             7489..8181
                     /protein_id="YP_492672.1"
                     /gene="ATP6"
                     /transl_table=9
                     /db_xref="GI:86990382"
                     /db_xref="GeneID:3912558"
                     /codon_start=1
                     /product="ATP synthase F0 subunit 6"
                     /translation="MNLNLNNIFGQFSPDIVALIPMTLIALAINLGWLSLTSSTNWLL
                     TRSGTLIQTFKQGTLSILFQQANPNIAPWIPAFTSVFIFILSVNVLGLLPYAFTSTSH
                     ISLTYSIGIPFWMSVNVLGFYLAFNSRLSHLVPQGTPPYLIPLMVIIETISLFAQPIA
                     LGLRLAANLTAGHLLIYLLSTAIWVLASSPLIAGITLSIFFLLFLLEIGVACIQAYVF
                     TALVNFYLAQNL"
     gene            8187..8969
                     /db_xref="GeneID:3912549"
                     /gene="COX3"
     CDS             8187..8969
                     /protein_id="YP_492673.1"
                     /gene="COX3"
                     /transl_table=9
                     /db_xref="GI:86990383"
                     /db_xref="GeneID:3912549"
                     /codon_start=1
                     /product="cytochrome c oxidase subunit III"
                     /translation="MAQSHPYHLVDQSPWPLTGAISALMMTSGLILWFHVNSNLLLIA
                     GTLLLTLTILNWWRDVIREATFQGSHTLPVNTGLRYGMILFITSEVCFFFAFFWAFFH
                     SSLAPTIELGVSWPPTGINPINPFLVPLLNTAVLLSSGVTVTWAHHSILAGNRTESIQ
                     ALFLTIALGIYFTTLQAWEYYDSPFTIADSVYGSTFFVATGFHGLHVLIGTTFLLVCF
                     IRLIFFHFSNNHHFGFEAAAWYWHFVDVVWLFLYVCIYWWGS"
     tRNA            complement(8968..9038)
                     /product="tRNA-Ser"
                     /note="codons recognized: UCN"
     gene            9066..9416
                     /db_xref="GeneID:3912553"
                     /gene="ND3"
     CDS             9066..9416
                     /protein_id="YP_492674.1"
                     /gene="ND3"
                     /transl_table=9
                     /db_xref="GI:86990384"
                     /db_xref="GeneID:3912553"
                     /codon_start=1
                     /translation="MYNFAITLTSILLITGLITTAAHALPSRNIDLEKSSPYECGFDP
                     LNHARIPFSFRFFLVAILFLLFDLEIALLFPFPVSTFFMSPNTSLGLAIAFLLILTLG
                     LAFEWSQGGLDWAE"
                     /product="NADH dehydrogenase subunit 3"
                     /transl_except=(pos:9066..9068,aa:Met)
     gene            9424..10806
                     /db_xref="GeneID:3912554"
                     /gene="ND4"
     CDS             9424..10806
                     /protein_id="YP_492675.1"
                     /gene="ND4"
                     /transl_table=9
                     /db_xref="GI:86990385"
                     /db_xref="GeneID:3912554"
                     /codon_start=1
                     /product="NADH dehydrogenase subunit 4"
                     /translation="MIYLILASSSSLILSWAVPRTLLWPSTIISSLILSSLTLNLAQN
                     HTSSLWHNISANFATDPLATPLIILSIWLGPLSLIASINTIKSLPLINQRTFISLIFV
                     ILTALILTLASLELTLFYIAFETTLLPTLILISRWGANKERYQASTYFLFYTLVGSLP
                     LLIAIISIYTTTNSSLLPTTSLNNNITSLPTTLTSLWWVFCLIAFVIKMPIYGFHLWL
                     PKAHVEAPIAGSMILAAVLLKLGGYGLTRTITIFVIPASINISFPLTTFCIWGALITS
                     IICLRQTDLKALIAYSSVGHMSLVASGIFSISLWGINGALTLMIAHGLISSALFCLAN
                     LLYERNTTRTLSITRGFKLVTPLLTVWWIITCVTNLGLPPTPNLIGELLIISTIIDWN
                     ILSTPIITTATIFGALYSLLILTNTNNNSFPSFITNTPPVTTSEHTLITLHLIPLTFI
                     ILNPSYILIN"
     tRNA            10815..10883
                     /product="tRNA-His"
     tRNA            10885..10952
                     /product="tRNA-Ser"
                     /note="codons recognized: AGN"
     gene            10953..12854
                     /db_xref="GeneID:3912556"
                     /gene="ND5"
     CDS             10953..12854
                     /protein_id="YP_492676.1"
                     /gene="ND5"
                     /transl_table=9
                     /db_xref="GI:86990386"
                     /db_xref="GeneID:3912556"
                     /codon_start=1
                     /product="NADH dehydrogenase subunit 5"
                     /translation="MVIEITSITTTINITIITILLISIFCFQSDLLPHKGLPNINFGT
                     LHDNKFSYTRNSSLFFSSILKSSALLSLIPLFLNINFDTPETIVSIAEWLPNNAHLIS
                     IELRFDLSFNLFFSVALFVSWSILEFSHYYMAQDPAPGNFFRLLIIFLLNMIILTSTN
                     NVFLLFIGWEGVGFLSFLLISWWTTRASANNSALQAVIYNRIGDIGILLFFSLSVTTF
                     NSWTLSEIFVLQPTNSLGNILLVWALIAAAGKSAQFGLHPWLPAAMEGPTPLSALLHS
                     STMVVAGIFLLIRRGPAYSDISAFNTWCLILGFITAILAATTAISQHDIKKIVAYSTT
                     SQLGLMMVAIGLNQPEIALFHVCTHAFFKAMLFLSSGSIIHSLKDEQDIRKMGGLYLI
                     LPNTTACIILGSLALSGTPFLAGFYSKDLILELGLSSLSNLTGIILALLATLLTAAYS
                     FRIIHFCFIGNPTFSPLSPTSEENTNLTNALNRLAAGTIISGWVISNFILQPPNITVS
                     LALKSLATLLTVSGIILTISLLHTLSLNMPPQNLINTNTFTTNQWFYEHTSHTILTTL
                     SFSLSLTGSTQSIDRGWSENLGAQGINLASSEISQNYQLAQTGYIKQYLLLSMSTFTV
                     IAIISAALL"
     gene            complement(12913..13401)
                     /db_xref="GeneID:3912557"
                     /gene="ND6"
     CDS             complement(12913..13401)
                     /protein_id="YP_492677.1"
                     /gene="ND6"
                     /transl_table=9
                     /db_xref="GI:86990387"
                     /db_xref="GeneID:3912557"
                     /codon_start=1
                     /product="NADH dehydrogenase subunit 6"
                     /translation="MVFYIVLVVMLLGSTLVFYSLSPYFGALGLVLVAVSGCVLCGFL
                     GSSFVALVLVLIYMGGMLVVFVYSTAISAERYPVVSNLNEVFLLSGVGVVWVFVSFDP
                     FLGFSLGGWSVVVESDLVGGGTLYNVLGGYLLVGGFVFLFALVVALVITYGAEYNILK
                     AL"
     gene            13416..14553
                     /db_xref="GeneID:3912550"
                     /gene="CYTB"
     CDS             13416..14553
                     /protein_id="YP_492678.1"
                     /gene="CYTB"
                     /transl_table=9
                     /note="TAA stop codon is completed by the addition of 3'
                     A residues to the mRNA"
                     /db_xref="GI:86990388"
                     /db_xref="GeneID:3912550"
                     /codon_start=1
                     /translation="MTGPLRKSHPLFNVVNNFLIDLPSPSNLSIWWNFGSLLGLCLII
                     QIITGLFLAMHYTSDISLAFSSISHICRDVNYGWLLRNIHANTASFFFLCIYFHIGRG
                     LYYGSYINKEAWNIGVILLLLTMLTAFVGYVLPWGQMSFWGATVITNLVSALPYIGTS
                     IVQWLWGGFSVDNATLTRFFAFHFLFPFIITALSIIHLFFLHQTGSNNATGIGSKFDK
                     TPFHTYFSYKDLTGFIALFTLISAIVLLSPTLLSDPENFNPANPLVTPVHIQPEWYFL
                     FAYAILRSIPNKLGGVIALLASILVLFMVPILHTSNNQASTFRPVSQSLFWCLTTIFL
                     FLTWIGSQPVEDPFILLGQIASTAYFSLFLLAIPLTSELENKLIF"
                     /product="cytochrome b"
                     /transl_except=(pos:14553,aa:TERM)
     tRNA            14554..14624
                     /product="tRNA-Phe"
     rRNA            14625..15552
                     /product="s-rRNA"
                     /note="12S ribosomal RNA"
     tRNA            15553..15621
                     /product="tRNA-Glu"
     tRNA            15630..15703
                     /product="tRNA-Thr"
     misc_feature    15703..16254
                     /note="putative control region"
BASE COUNT     5136 a   4605 c   2486 g   4027 t
ORIGIN      
        1 agatagaaac tgacctggct cacgccggtc tgaactcaga tcacgtagga ttttaatggt
       61 cgaacagacc aaccctcagg aactactgca cccctaggca atcccgatcc aacatcgagg
      121 tcgcaaactc ccttatcaat aagaactctc caagagaatt acgctgttat ccctacggta
      181 acttactcct ttaatcgccc tcttcccggc ggatccccac aaaggcaacg cccgcacaga
      241 agccgacact tcacgaatgc tccgaaaacg gagggtaact attctccgca gttgccccaa
      301 ctaaagcaac aagcacacag ccaggccacc tgatcggtaa actcacctcc tccaaaagaa
      361 gacgattagc ccccaaacag ccaaaccaac ttgtgcaacc cactaaagct cgatagggtc
      421 ttctcgtccc acgactacac ccccgcttct tcacgaggat atcaaattca agatttgagt
      481 aggagacagc tggacctccg tcttgccatt cataccagcc cccatttaaa gggcaaatga
      541 ttatgctacc ttcgcacggt caagataccg cggccgttta actaagtcac cgggcaggca
      601 ggacccttta tacataagaa aactttacaa agggcgatgt ttttggtaaa caggcgagat
      661 ccttgatttg ccgaattcct tctcctcaat tttataacct ttccgagcca cttgagttag
      721 cagacagaca aagacgagct acactttctc gcacattgaa gctcctccca tcaaaaatta
      781 ggactgctta acacacaaaa agccacttta ctctttacta atcccagcat tataactccc
      841 ataatagtat gagacttccc cataaataac cacggcataa aactcacctt gccaaaatat
      901 acatacacgc cactggctac aaaacgagct ttaacgccct catccggata gatgccatta
      961 atcctaccac tagtcagaac ccaattaacg tgtttcccag cgcgttttta acccatggtt
     1021 aaggctttta cctcctcaac aaggaagctt atccctcctt gtctacactc cgaatttcta
     1081 tcaaggatta actattacct cttacggata attacatccc caatagccaa acaaatatag
     1141 ctgacaccaa tttccgggga aaccagctat cattgagcac gataaacatt tcacacctag
     1201 tgtaccctcg aaccttacta ttgcaacagt aaaagctttc ttctcacaag gaagagtaca
     1261 ctaactcgct caaattcggg tacggcaact cctcaccaga atactcaccg aaccatcata
     1321 caaaaggtac aggacttcat cctttcttct ttacccttaa atgtttcacg atatttcaac
     1381 tttccctcac ggtactaccc ctttagctct cactacaagt ttcactgaca acctactact
     1441 cccacttgtt ccaaactatc aatattttga taaacctaaa acatcacggt tttattcttt
     1501 cttcacctct ataaggctag cctttaaaaa tctaattact ccacacaaaa tctacaacaa
     1561 ggaaacaaac acagggaaac tcaccaagcc tagtaaactc accctcaaac cccaacaaag
     1621 aattagaccc cgagccgtag gaacacccaa tcccccatcc tgcagccctc gccagccaaa
     1681 gagaactaga gaatgctgag gaaacaacaa caagctcctt ttaaaggaca cacgaagata
     1741 aaagaacaag ctaagcagac tccctgcaac taaaaaacct cttaccagaa cactacccct
     1801 ttcaagaaga cacttcagag agacgaactt tattaggaag ccgaaaagag gaggcaaaac
     1861 ccccagggaa agcacaccca aaacaatacc ggaactcttc ccaacattaa agtatgaaac
     1921 acgacctaca tgagctaaag tcttcaaatc aaattctctc gcaatcaaaa acaccctgga
     1981 attagtaatt atgtaaatca gcaacataac acaaccggca ttagcagaat accccacagt
     2041 tgagcaaatc caccccatat gtgccaccga tgaaaaagcc aaaatcttcc gcacctgcgt
     2101 ctgattcaaa cctccccacc cacctattag cacagaaaac acagccagac atgacaatac
     2161 tcgaatatct accctatcaa tcacatacac caaaacagaa aaaggggcca gcttctgcca
     2221 agttgacaga accaaaccct ctaagaagcc aaccccctgg acaacatctg gaaaccagta
     2281 atgacacgga aagagcccca acttgagacc tatggccaga gtgatcaata aggaagaaac
     2341 cttaagcagg ggttggccaa ccaaccacga agaactaaac caagcttgta taacaacaac
     2401 attaagtata acagcagccc tcacggactg caccaaaaaa tacttcacgg acgactctac
     2461 cttccggggt aaaaaccccc cacacagaat gggcaaaata gataaagtat tcacctccaa
     2521 tcccacccac aaagtaaacc agtgatggct tcttaaaaca acaaaagtcc caaagacaac
     2581 tctaacaacc aacacaataa aaaccctacg atgcataaaa cctggaagga atttaacctt
     2641 cagcaaccta attatcagct aggaacccct acttcagggt acaggttcta tactaagacc
     2701 aaactaggtg gcaaaatatc aacagaaact aacaacaccc tataaaatac taacactcct
     2761 aaactcaagg gtaaatactt cttccaagtc aagtacatca aatggtcata tcgaaaccga
     2821 ggataagatg cccgaactca tagaaacaag acaaccaaaa atatagtctt taccctcacc
     2881 attagaaccc ctacagggaa aacaccccta aaaggactcg aacccccaaa aaagaggacc
     2941 actgaaagta aattcataaa aattattttc ccgtattctg ctataaaaaa catagcaaaa
     3001 ggcccaccag catattctac tttataccct gaaacaattt ccgactcccc ctccgtcaaa
     3061 tcaaagggag cacggttagt ctcggctaat gtagaaacaa accataccac aaacaaaggt
     3121 aagcaacaaa agaccaacca agaacctccc tgactttttt cgatgaccct aaggctgaag
     3181 ccccccgaga acactactac ccctaatagg atcaacccta aacttatctc ataagagacc
     3241 gtttgagcaa cagcccgaac agcccccaaa aaggaataat tcgaattaga tgcccagccc
     3301 gatcccagca aagcataaac agacaacctg gataacccca tcactaaaac aagcgacaat
     3361 ttaacctcca acacacaaaa gccgactgga ataagtgacc acaagaaaag cgcaatccct
     3421 agaaaaagaa taggagacaa aaaaaacaaa taaggcgaag ctttagaagg ctttaaagtc
     3481 tcctttatca acagcttgaa cccgtctgct atcggttgta ataaaccaaa cggccccacc
     3541 acattaggcc ccttacgaaa ttgcatataa ccaaggacct ttcgctccac taaagtcaac
     3601 aaagccactg ccagcagcac cggaattata aaaacaactg atttagtaat aaaaactagc
     3661 ccctccacag ctaaagaaag gactcgaacc ttccatagag aaaccttaga cttcttgcat
     3721 taccactttg ctacttcagc tatttctata tataaggatt atctgacata cttcacctct
     3781 gattacaaac agagacccct tagttggaag ccaagaatac tgatgtactc gtgaagtcta
     3841 gcgagaggag gaatcaaacc ccccttcttg gatttacaat ccaccacact aacctctgcc
     3901 atctcgccaa agagctagtt aaaccgataa caccagaatg tcagactgga attgctggct
     3961 gataacccag cgctctttga aataaaggga ggtatctatc cttccatttt tggggtatga
     4021 acccaaaagc ttctattagc ttactttact tacatccttt ctaggttaga gcttgaccaa
     4081 gcatctcttt tacacggaga agatatctgc gcaaaccaga ttaccttgaa agttctggcg
     4141 gatgttaccc gcatctatag atttgcaatc taaaatgtta attacactac aaaacccagg
     4201 ggttaaaaaa ctttcatttt tatttaaagc tttgaaggct atcagtttta attaacttaa
     4261 acccctcatt agtgaattta gtttaataaa aacatttgac ttgcacttaa aaactctaag
     4321 tttaaacctt agaattcaca aactaagaga aggaattgaa ccttcgatat tagatcctaa
     4381 atctaatgca gtaaccactt tgctatccta accctgagtc gacaagtatc gatcttgtta
     4441 tctcctggtt aacggccaat tgccttccca ttaggctacg acccaaatag aaagtagttt
     4501 aacaggtaaa acaaagaatt ttgatttctt caacataagt tcaaccctta tctttctagt
     4561 cagaaaaata ggactccaca cctataccag caactcccaa agctaccatt ctcactaaac
     4621 tattttctgt ttaccctata tataataaaa ttataaacca tgcaactgag gcgatgattt
     4681 ttttcaacaa aacacaagga cattggaaca ctatatctaa tattcggagc ctgggcagga
     4741 atggttggaa ctgccatgag agtaataata cgaacagaac tggcccaacc aggatcactc
     4801 ctccaagacg accaaatata caacgtaata gttacggccc acgccctagt aatgatattc
     4861 ttcatggtaa tgccaatcat gattggcgga tttggcaact gactaatccc cttaatgatc
     4921 ggagcacccg atatggcctt tccccgaatg aacaacatga gcttctggct agtccccccc
     4981 tccttcctgc tactcttagc atcagccgga gttgaaagag gtgctggaac cggatgaacc
     5041 atctaccctc cactgtctag tggcctagcc cacgctgggg ggtcagtaga ccttgcaata
     5101 ttttccctcc accttgcagg agcatcctct atcctagcct ccataaaatt catcactact
     5161 gtcattaaca tgcgaacccc tggtatctca ttcgaccgcc taccattatt tgtctgatct
     5221 gtattcgtga cagcattctt actcctcctt tcccttcccg ttctagctgg agccataacg
     5281 atgctcctca ctgatcgaaa agtgaacaca accttcttcg acccagcagg aggaggggac
     5341 cctattctat tccaacacct tttctggttc ttcggacacc ctgaagtcta cattctcata
     5401 cttccaggat ttggaatgat atcccatgta attgctcact actcaggtaa gagagaacct
     5461 tttggttacc taggtatggt ctacgctata gtatctattg gaatactagg gttcctggtg
     5521 tgagcccacc acatgtttac agttggtatg gacgtagaca ctcgagcata ctttacggct
     5581 gcaacaatga taatagctgt gcccacagga attaaggtct tcagatggat ggcaacacta
     5641 caaggcagaa accttcgatg agacacacca ctactttggg ccctcggatt tgtattctta
     5701 tttaccatag gaggactaac gggtgtaatc ctagcaaaat catccatcga cgtaatcctc
     5761 cacgatactt actacgtagt cgcccacttc cactacgtac tgtcgatggg agcagtattt
     5821 gctatctttg caggatttac acactgattc cccctcttct caggagtagg acttcacccc
     5881 ttatgaggaa agatccactt cgcattaatg tttataggag taaacctcac tttctttccc
     5941 cagcacttcc tgggactagc cggtatgcca cggcgatact ctgattaccc agacgcatac
     6001 accctttgaa acactatctc atccataggc agcaccatat ccctcgtagc aacgctgata
     6061 ttcttattca ttatttggga agccttcacc tcccaacgaa caacaattca acccgaattt
     6121 gcaccttcct cactagaatg gcaatactcc tcctttcccc cctcccatca taccttcgac
     6181 gaaattccag caactgtata cttaattaag tatgaggatt agtttaataa aaacctttga
     6241 cttcgactca aaaaacttca gttacaccct gaaatccttt tattacaccc atctttatta
     6301 gtactatatc catattttac ctaggattac taccaatatt ttttaaccgg ctacacttct
     6361 tatctatcct gctctgcctg gaactcctcc taatatcact attcctaaga ataacaatat
     6421 gagcactaaa agccggaacc aacttcttcg tggcaaaaaa cctcatcctt cttacccttt
     6481 ctgcctgcga agcaagagcc ggactctccc taatggtagc actctcacga actcacaaat
     6541 tagacttagt tatagcacta aacatattac aacaataaat ggcaaattgg acccaactag
     6601 gactacaaga cgcatcttcc cccctgatgg aagaactaat ctactttcat gactacaccc
     6661 taatcatcct cactctaatc acaatactag tcttctacgg attggcatcc ctgctattct
     6721 cctccagaac aaaccgattc tttttagaag gacaaggatt agaaaccata tgaacaatca
     6781 tccctgccat catcctcata tttatagcac tcccatccct ccaacttctc taccttatgg
     6841 acgaggtaaa aaaccccttc ctcactataa aggcgatagg acaccaatgg tactgaagat
     6901 acgaatacgc agattaccgt gaattagaat ttgactcata catgattcct acttcagacc
     6961 tttcctccgg catgccccgc ctactaaaag tagacaaacg attgatactg cccgcccaaa
     7021 cgccaatccg cgtattagta tcctccgcag acgttctcca ctcctgggca aacctttccc
     7081 taggagtaaa gatggacgcg gtaccaggac gactaaacca ggtaaaattt ttcatttccc
     7141 gatgcggcat attctatggc cagtgctcag agatttgcgg agcaaaccat agattcatgc
     7201 ccatagttat tgagaccaca aaattttcct catttgaaac atgggtatct aacttcctaa
     7261 cagaatcttt ggtaagctaa tacggaagca tcaaactctt gacttgaata aaagtggaga
     7321 cccgcccact accaaagaaa tgccacagct aaacctagct tgatgactat ttaaattctt
     7381 aattagatga gcaacattac ttgtagtctt tactgcctta ctcagcacac ccccaataga
     7441 aaagcctacc aaaatcacaa cccaaactaa gttacacccc ttaaaaaaat gaacctgaaa
     7501 ctaaaaaaca tattcggcca attctccccg gacatcgtag ccctaattcc catgaccctc
     7561 atcgccttgg ccattaacct aggatgactc tctctaacaa gaagaacaaa ctgactcctc
     7621 acccgaagtg gaactttgat ccaaaccttc aagcagggaa ctctaagaat actattccag
     7681 caagccaacc ccaaaattgc accctgaatc ccagccttta cctctgtatt tatattcatc
     7741 ctatcagtaa aagtattagg actactaccg tatgccttca cttctaccag ccacatatca
     7801 cttacttact ccataggcat tcccttctga atgtccgtca acgtccttgg attctatcta
     7861 gcattcaaaa gtcgactaag acacctagta ccccaaggta ctccccccta cctaatcccc
     7921 ctgatggtaa taatagaaac aatcagacta ttcgcacaac ccatcgcctt gggcctacga
     7981 ttagccgcca acctaacagc agggcatctt ttaatatacc tcctctccac agcgatttga
     8041 gtcctagcaa gatcccccct tatagctgga ataaccctct caatattttt cctcctattc
     8101 ttactagaaa taggagtagc ctgcattcag gcctacgtgt ttaccgcact agttaaattc
     8161 taccttgccc aaaacctata aaaatcatgg cccaatcaca cccataccac ctagtagacc
     8221 aaagaccctg acccctcact ggggctatta gtgccctcat gatgacctcc ggtctgatac
     8281 tgtgattcca cgtaaaaaga aacttactgc taattgcagg aactctactt cttaccctaa
     8341 ctatcctaaa atgatggcga gacgtaatac gggaagccac gtttcaaggc agacacaccc
     8401 taccagttaa cactggacta cgatacggta tgatactttt tattacctca gaagtttgct
     8461 tcttcttcgc tttcttctga gcattcttcc acagcagcct agcaccaacc atcgaactag
     8521 gcgtatcatg accccccact ggaataaacc caatcaaccc ctttctagtc cctcttctta
     8581 acactgccgt cctactctca tccggggtaa cagtcacttg agcccaccac agaatcctag
     8641 ccgggaaccg cacagaatcc atacaagccc tattcctaac tatagcccta ggtatatact
     8701 ttaccaccct acaagcctga gagtattacg actccccatt taccatcgcc gacagagtgt
     8761 atggctctac attttttgta gccaccggct tccatgggct ccacgtactc ataggaacaa
     8821 ctttcctctt agtatgcttc atacgactaa tattcttcca cttttccaat aaccaccact
     8881 ttggcttcga agcggccgcc tgatactgac acttcgtaga cgttgtatga ctattccttt
     8941 acgtctgcat ctattgatga gggtcctaag agaagaaagg actcgaacct ttatctttct
     9001 agtttcaagc taaacgcatc ccgctctgcc acttctcccc aaaaatcctt atatacccaa
     9061 taaaaattta caaatttgcc atcaccctga catcaatcct cctgataaca ggattaatca
     9121 ccaccgcagc ccacgcccta cctagccgaa aaatagacct agaaaagtcc tcaccctacg
     9181 aatgtgggtt tgaccctttg aaacacgcac gcataccatt ctctttccga tttttcctgg
     9241 ttgccatctt atttctccta ttcgacctgg aaattgccct attattcccg ttccccgtaa
     9301 gaacattctt tatgtcccct aaaacctcac taggactggc aatagcattc ctactaatac
     9361 ttacacttgg gctagccttc gaatgatctc aagggggtct cgactgagcc gaataagaaa
     9421 ctaatgatat atcttatctt agcctcctcc tcaagcctca tcctatcctg ggctgtgccc
     9481 cgaacactac tatgaccctc aaccataatc tcttcgctta tcctctccag gctaactctt
     9541 aacctagccc aaaaacacac atcttcgtta tgacacaata tctccgctaa cttcgccacc
     9601 gaccctctgg ccacacccct aataatccta agcatatgac ttggcccttt gtcccttatt
     9661 gccagaataa aaacaataaa gagcctacca ctaataaaac agcgcacctt catttctcta
     9721 atatttgtta tcctcactgc cctaatcctc acgcttgcct cactcgaact aaccctattc
     9781 tacatcgcat ttgaaacaac ccttcttcca acgctaattc tcatatcccg ctggggggcg
     9841 aaaaaggaac ggtaccaggc cagtacatac ttccttttct atactctcgt gggttcccta
     9901 cccctactca tagccatcat aagcatttac accacaacta aatcatccct actacctact
     9961 acttccctta aaaaaaaaat aacatcacta cccaccacac taacctctct atgatgagtc
    10021 ttctgcctca tcgcctttgt aataaagatg ccaatttatg gattccacct ttggcttccc
    10081 aaggcccatg tagaggctcc tatagctggg tcaatgatcc ttgcagccgt acttctaaag
    10141 ctagggggat acggactcac acgaactatt acaatatttg ttatacccgc ctctataaaa
    10201 atatcctttc ccctcacgac cttctgcata tgaggcgccc taataacaag aataatctgc
    10261 ctccgccaaa cagacttaaa ggccttaata gcctactcat ccgtgggcca catgaggtta
    10321 gtagcttccg gcatattttc aatatcccta tggggaataa aaggtgccct cactctcatg
    10381 attgcccatg gattaatatc ctcagccctg ttttgccttg caaaactcct gtacgaacga
    10441 aacaccacac gtaccctatc aataacccga ggtttcaagc tagtgacccc actactcact
    10501 gtatgatgaa taataacgtg cgtaacaaac ctaggacttc cccctactcc taacctaatc
    10561 ggggaactcc ttatcatatc cactattata gactgaaaaa tcctatccac acccataatt
    10621 accacggcaa caatatttgg agccctctac tccctcctta tattaactaa caccaataaa
    10681 aactccttcc caagctttat tacaaaaact cccccggtaa ccacttcaga acacacccta
    10741 ataacccttc atcttatccc cctaacattc atcatactta aaccctccta catactaata
    10801 aaatagcacc cacgactaaa gtagtttaat aaagacacta atttgtggca ttagaattgc
    10861 cagttaaaac ctggcctata gtccgaaact tattggctta ttctagtcct gctaagtcca
    10921 agaatctgta gttcaattct atagaagttt cgatggtaat agaaatcaca agaataacca
    10981 caaccataaa aatcacgatc ataaccatac tgcttatctc catattttgc tttcaaagcg
    11041 atctattgcc ccataagggg ctacctaaca tcaacttcgg aacacttcat gacaaaaagt
    11101 tcaggtacac acgcaaaaga agactattct tctcatctat actaaagaga tcagccctcc
    11161 tttcactcat acccctcttt ttaaaaataa aatttgacac cccagaaaca atagtttcca
    11221 tagccgaatg attacccaaa aacgcacacc tcataagtat tgaactacga tttgaccttt
    11281 cattcaaact attcttttca gttgcattat tcgtctcttg atcaatccta gaattctcac
    11341 actactacat ggcacaagac ccagcaccag gcaaattctt ccgtctctta ataattttcc
    11401 tactaaaaat gatcatactc acctccacta aaaacgtatt ccttctgttt ataggctggg
    11461 aaggggtcgg attcttatca ttcttattga taaggtggtg aaccacacga gcaagagcaa
    11521 aaaaatctgc cctccaagca gtaatataca accgaatagg agacataggc atccttttat
    11581 ttttctccct gagggttaca acctttaatt cctggaccct atcagagata tttgtcctac
    11641 agcccacaaa ctctctaggg aatattttac tagtttgggc cctcatagct gctgcaggga
    11701 agtccgccca attcggacta cacccctgac tcccagcagc catggaggga cccacccctc
    11761 tatcagccct cctccacagc tctacaatgg tagttgcagg aatattccta ctaatccgcc
    11821 gtggcccggc ctattcagac ataagagcct ttaaaacatg atgcctgata cttggcttta
    11881 tcacagcaat attggctgca accacggcca tatcccagca cgacataaag aagattgtag
    11941 catactccac caccagacaa ctaggactca tgatggtcgc cataggccta aaccaaccag
    12001 agatcgcact attccacgtt tgcacacacg cattctttaa ggcaatgcta ttcctatctt
    12061 ctggcagaat tatccacaga ctaaaggacg aacaagacat acgaaagatg ggaggactct
    12121 acctgatact ccctaacaca actgcctgca ttattctagg gagacttgcc ctctctggta
    12181 caccattcct tgctggattc tactccaagg acctaatcct agaactgggc ctctctagac
    12241 tatcaaacct aacgggaatt atcttagctc tcttggcaac ccttttgacc gcagcttact
    12301 cattccgcat tatacatttc tgcttcattg gaaacccgac cttctcaccg ctctccccca
    12361 ccagagaaga aaaaactaaa ctaaccaaag cattaaaacg actagccgct ggtacgataa
    12421 tatcaggatg ggtaatatca aacttcatcc tgcaaccacc caaaatcacc gtcagactcg
    12481 cccttaagag tctggccacc ctattaaccg tctccgggat aatattaaca atatcactgc
    12541 tccacactct ttccctaaaa atgccccccc aaaacctcat aaacaccaaa acgttcacca
    12601 caaaacaatg attctacgaa cacacgtccc acactatact cacaaccttg tctttctcgc
    12661 tctccctaac aggaaggacc caaagaatag accgagggtg aagagaaaac ctgggcgcac
    12721 aaggaataaa tctagcttct tcggaaatct cccaaaaata tcaactggcc caaacaggct
    12781 acattaagca ataccttctc ctttccatgt ccacctttac tgtcatagcc ataatctccg
    12841 ccgctctcct ataatagcca agccagcgga aactataatt atactcgata acaactaaat
    12901 atatagctag ctctacaggg ccttcaatat tttatattcc gccccataag taatcactag
    12961 tgcaactact aaagcaaaca agaatacaaa cccccctact aacaaataac cccccaatac
    13021 tttatacaaa gtaccacccc caacaagatc cctttctact accacagacc accccccgag
    13081 cgaaaagccc aagaaaggat caaacctgac aaaaacccaa acaacgccca cgccccttaa
    13141 gagaaacacc tcattcaaat tactcactac tgggtaccgc tctgcagaaa tagccgtaga
    13201 ataaacaaaa acaaccagca ttccccccat ataaataaga acaagcacca gagccacaaa
    13261 agaggaccca agaaacccgc aaaggacaca ccccgacacg gccactaaaa ccaggcctag
    13321 ggcaccaaaa taaggggaca acctataaaa caccagagta cttcccaaaa gcataacaac
    13381 caatacaata taaaaaacca ttatatatag aaatcatgac aggccctctc cgaaagagac
    13441 accccctatt taaagtagtg aaaaattttc taatagacct cccctcccct agaaaactat
    13501 ccatatggtg aaaatttgga tccctattag gcctttgcct aattatccaa ataatcacag
    13561 gcctatttct agctatgcat tatacctcag acatttcctt agccttctca tccatcagcc
    13621 acatatgccg agacgtaaac tacggttgac ttctacgaaa tattcacgcc aaaaccgcct
    13681 ctttcttttt cctttgcatt tattttcaca taggccgagg attatactac ggctcctaca
    13741 taaaaaagga agcctgaaaa ataggcgtca tactccttct cctcactatg ctaacagctt
    13801 tcgtcggata cgtcctcccg tggggtcaaa tgtcgttttg aggagcaaca gtaatcacaa
    13861 acctcgtgtc tgcccttccc tacataggga catcaatagt ccaatgactt tggggtggat
    13921 tctcagttga caacgccact cttacccgat tctttgcctt ccacttcctg ttccctttta
    13981 ttatcaccgc tctctcaatc atccatctat tcttcctcca ccaaaccggt tccaacaaag
    14041 ccacagggat aggatcaaag tttgataaga ctccgttcca cacatacttt tcttacaagg
    14101 acctaacagg gtttatagcc ttatttaccc taataagcgc aatagttctt ctatccccaa
    14161 ctttactcag agaccctgaa aaattcaaac ctgccaaccc cctagttaca ccagtccaca
    14221 tccaaccgga atgatacttc cttttcgctt acgcaatcct tcgatctatc cctaaaaagt
    14281 tagggggcgt aatagcccta ttagcatcaa tccttgtttt attcatggtc ccaatcctcc
    14341 atacatcaaa taaccaagcc agtacctttc gacctgtttc acagagactc ttctgatgtc
    14401 tcaccaccat cttcctgttc ctaacgtgaa tagggagaca acccgtagaa gacccattca
    14461 tcctccttgg acaaatagcc tcaacagctt acttctcctt attcctgctt gcaattcccc
    14521 taacgtcaga actagagaaa aagctgatct tctgcaaaga tagcttaata gaaaagcaaa
    14581 gcactgaaaa cgcttaaata aaggttcgag tccttttctt agcaaccgat ttggtcctag
    14641 tccttccctc aactttctcc aggatgatac atgcaaagcc ctcaattcta cggtgagctc
    14701 aatctgcttc tggtctcccc cgagatacca gaacaccaaa aatagcatca ggttaccgcc
    14761 tatcgtaacc caagacgcta aggccagcca aacaaaaata gcccacacct gcagtacttg
    14821 acattacaca ataagcgcta gcttgatgta gccatagagg aaaaaaccgg taaattatgt
    14881 gccagccacc gcggttatac ataagatttt agttgagggc ctcggtaaaa aggtgataaa
    14941 acagcaccag agtcctcgcc ccctcaagca gtagtaagct aacaggaccc taagaactat
    15001 cctaccaaac cctgccctat ccaaaccctt aagattcatc accaaagctc aaagataaac
    15061 tgggattaga taccccatta tatgagccct aaaacaactt aagcacctga gaactacgaa
    15121 caaaagttta aaactcaaag gacttggcgg ttttctagac ctccctggag gagcttgcta
    15181 tctaaccgat aacccacgaa acacctcacc agcctttgca aaccgcagcc tgtataccat
    15241 cgtcgtcagt ctacccttta aagacagtat acctaatgga gtgatctcca tatcctcctc
    15301 cacgtcggat cgaggtgcag ctaataggcc ggggataagt gagctacaat aactaatcaa
    15361 cacacccttt aagccaacat atggacaagc ccatgaaaac cgggactcaa aacaggattc
    15421 agcagtaacg cctacaaggg aataggtgtg aagcacacag ctctagaatg cgcacacatc
    15481 gcccgtcact ctcgtctaca gaggagaaaa gtcgtaacaa agtaggcgta ttggaaaatg
    15541 cgcctggtac aaattcttat agttgagcca caacagcagc ttttcacgct acaagcttgg
    15601 gttagacccc caataagaat tacgcgacca gcctcaaaag ctaacgggta agcaattaat
    15661 cttgtaaatt aaaaggcgaa ggttcgagtc ctttttgagg ctccccataa cccccccccc
    15721 ccccctccgg gggggttata ctcgcataag cttgtgttct aggaaagcta tatagggcca
    15781 aggcgttatg agaccttcct tatggggcaa tagatcgctt tgaaagcata ggcaaaatcc
    15841 cttatttctt atatttccgc tccgcggggg atagttgggg taaggctaca ttagctggaa
    15901 ccacgtccag gtgtttccct tcttactttg acaagctcct ttctgctaca ggattataaa
    15961 ccaaatgaca attggacaca atccaccata ggtccctagg cccctacagc actgagtccc
    16021 cttacaacca cgaaagacca aaacaaaact cagggccatg caaccgtgcc ccataaacga
    16081 gacttaaacc agactctttt attcttctta ctacctgaaa tcgacctaca accacaggca
    16141 tcaaaaccac aatctttatt ttacaacaga accttaaaag gtgtttacct taaagcattg
    16201 acaccacccc tccaatcctt tcgtactaag aggagccctt atttccataa tcgt
//
