LOCUS       NC_007788              16234 bp    DNA     circular INV 04-APR-2006
DEFINITION  Acanthaster planci mitochondrion, complete genome.
ACCESSION   NC_007788
VERSION     NC_007788.1  GI:86990333
KEYWORDS    .
SOURCE      mitochondrion Acanthaster planci (crown of thorns starfish)
  ORGANISM  Acanthaster planci
            Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Asterozoa;
            Asteroidea; Valvatacea; Valvatida; Acanthasteridae; Acanthaster.
REFERENCE   1  (bases 1 to 16234)
  AUTHORS   Yasuda,N., Hamaguchi,M., Sasaki,M., Nagai,S., Saba,M. and
            Nadaoka,K.
  TITLE     Complete mitochondrial genome sequences for Crown-of-thorns
            starfish Acanthaster planci and Acanthaster brevispinus
  JOURNAL   (er) BMC Genomics 7 (1), 17 (2006) PUBMED   16438737
REFERENCE   2  (bases 1 to 16234)
  AUTHORS   
  TITLE     Direct Submission
  JOURNAL   Submitted (08-FEB-2006) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 16234)
  AUTHORS   Yasuda,N., Hamaguchi,M., Sasaki,M. and Nadaoka,K.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2005) Tokyo Institute of Technology, Graduate
            school of Information Science and Technology; O0okayama 2-12-1,
            Meguro-ku, Tokyo 152-8552, Japan
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AB231475.
FEATURES             Location/Qualifiers
     source          1..16234
                     /mol_type="genomic DNA"
                     /db_xref="taxon:133434"
                     /country="Japan: Ryukyu Island, Akajima"
                     /tissue_type="tube foot"
                     /organelle="mitochondrion"
                     /common="crown of thorns starfish"
                     /organism="Acanthaster planci"
     rRNA            complement(1..1549)
                     /product="l-rRNA"
                     /note="16S ribosomal RNA"
     gene            complement(1556..2620)
                     /db_xref="GeneID:3907680"
                     /gene="ND2"
     CDS             complement(1556..2620)
                     /protein_id="YP_492653.1"
                     /gene="ND2"
                     /transl_table=9
                     /db_xref="GI:86990334"
                     /db_xref="GeneID:3907680"
                     /codon_start=1
                     /product="NADH dehydrogenase subunit 2"
                     /translation="MHRSVFIVLVISVVFGTFIVLSSHHWFTLWVGLEVNTLSILPIL
                     CGGFLPRKVESSVKYFLVQSVSAAVILNVVVIQAWFSSSWLVGQPLLSVSSVLITLAV
                     GLKLGLFPCHYWFPDVVQGVGFLEGLVLSTWQKLAPFSVLVYVINSVDIRVLVCLGVL
                     SVLIGGWGGLNQTQVRKILAFSSVAHMGWICSTVGYSVNAGCIMLLVYVITNSSVFLI
                     ASEFDLKTLSHVGRLSYFSLGGSAGMVLGVLSLGGLPPLFGFLIKFVSLKCLLESGSI
                     LASGFLVAGSLLSLFYYLRVSFNSSLVLFPQHSLVLFGWRGLLGGNSGAVTVRGLVLC
                     GGLSVSLLGLVSLPVFASLL"
     tRNA            complement(2621..2692)
                     /product="tRNA-Ile"
     gene            complement(2692..3672)
                     /db_xref="GeneID:3907679"
                     /gene="ND1"
     CDS             complement(2692..3672)
                     /protein_id="YP_492654.1"
                     /gene="ND1"
                     /transl_table=9
                     /db_xref="GI:86990335"
                     /db_xref="GeneID:3907679"
                     /codon_start=1
                     /product="NADH dehydrogenase subunit 1"
                     /translation="MDGLVFIVNSVVFIIPVLLAVALLTLVERKVLGYMQFRKGPNVV
                     GPFGLLQPLADGFKLLIKETLKPSNASPYLFFLSPILFLSIALFLWSLIPVGFCVLEV
                     NLSLVLVMGLSSLSVYALLGSGWASNSNYSFLGAVRAVAQTVSYEISLGLILLGVVVF
                     SGGFSLSVIENSQGGSWLVFCCSPLFVVWFVSTLAETNRAPFDLTEGESEIVSGYNVE
                     YAGGPFAMFFIAEYGNIIFMNLLSVVLFFGGSSPFGGVFPMGVLIVSVKTVFLVVLFL
                     WVRASYPRFRYDHLMYLTWKKYLPFSLGVLVFYSVLLVSVDILPPSLVLV"
     tRNA            complement(3673..3744)
                     /product="tRNA-Leu"
                     /note="codons recognized: UUR"
     tRNA            complement(3773..3841)
                     /product="tRNA-Gly"
                     /note="re-annotated by tRNAscan-SE"
     tRNA            complement(3843..3912)
                     /product="tRNA-Tyr"
     tRNA            3913..3983
                     /product="tRNA-Asp"
     tRNA            complement(3985..4055)
                     /product="tRNA-Met"
     tRNA            4067..4134
                     /product="tRNA-Val"
     tRNA            complement(4135..4201)
                     /product="tRNA-Cys"
     tRNA            complement(4202..4271)
                     /product="tRNA-Trp"
     tRNA            4277..4345
                     /product="tRNA-Ala"
     tRNA            complement(4346..4417)
                     /product="tRNA-Leu"
                     /note="codons recognized: CUN"
     tRNA            complement(4418..4489)
                     /product="tRNA-Asn"
     tRNA            4492..4563
                     /product="tRNA-Gln"
     tRNA            complement(4564..4634)
                     /product="tRNA-Pro"
     gene            4665..6217
                     /db_xref="GeneID:3907688"
                     /gene="COX1"
     CDS             4665..6217
                     /protein_id="YP_492655.1"
                     /gene="COX1"
                     /transl_table=9
                     /note="TAA stop codon is completed by the addition of 3'
                     A residues to the mRNA"
                     /db_xref="GI:86990336"
                     /db_xref="GeneID:3907688"
                     /codon_start=1
                     /translation="MQLSRWFFSTNHKGIGTLYLIFGAWAGMVGTAMSVIIRTELAQP
                     GSLLQDDQIYNVIVTAHALVMIFFMVMPIMIGGFSNWLIPLMIGAPDMAFPRMNNMSF
                     WLVPPSFLLLLASAGVESGAGTGWTIYPPLSSGLAHAGGSVDLAIFSLHLAGASSILA
                     SINFITTVINMRTPGISFDRLPLFVWSVFVTAFLLLLSLPVLAGAITMLLTDRNVNTT
                     FFDPAGGGDPILFQHLFWFFGHPEVYILILPGFGMISHVIAHYSGKSEPFGYLGMVYA
                     IVSIGILGFLVWAHHMFTVGMDVDTRAYFTAATMIIAVPTGIKVFSWMATLQGSNLRW
                     DTPLLWALGFVFLFTIGGLTGVILANSSIDVILHDTYYVVAHFHYVLSMGAVFAIFAG
                     FTHWFPLFSGVGLHPLWGKIHFALMFIGVNLTFFPQHFLGLAGMPRRYSDYPDAYTLW
                     NTISSIGSTISLVATLIFLFIIWEAFTSQRTTVRPEFAPSSLEWQYSSFPPSHHTFDE
                     IPATVYLIK"
                     /product="cytochrome c oxidase subunit I"
                     /transl_except=(pos:6216..6217,aa:TERM)
     tRNA            6218..6286
                     /product="tRNA-Arg"
     gene            6287..6583
                     /db_xref="GeneID:3907683"
                     /gene="ND4L"
     CDS             6287..6583
                     /protein_id="YP_492656.1"
                     /gene="ND4L"
                     /transl_table=9
                     /db_xref="GI:86990337"
                     /db_xref="GeneID:3907683"
                     /codon_start=1
                     /translation="MTPIFISTISIYYLGLLGILINRLHFLSILLCLELLLISLFLSM
                     TIWALNTGTNLFVANNLILLTLSACEASAGLSLMVALSRTHNSDLVIALNILQQ"
                     /product="NADH dehydrogenase subunit 4L"
                     /transl_except=(pos:6287..6289,aa:Met)
     gene            6584..7271
                     /db_xref="GeneID:3907676"
                     /gene="COX2"
     CDS             6584..7271
                     /protein_id="YP_492657.1"
                     /gene="COX2"
                     /transl_table=9
                     /note="TAA stop codon is completed by the addition of 3'
                     A residues to the mRNA"
                     /db_xref="GI:86990338"
                     /db_xref="GeneID:3907676"
                     /codon_start=1
                     /translation="MANWTQLGLQDASSPLMEELIYFHDYTLIILTLITILVFYGLAS
                     LLFSSSTNRFFLEGQGLETIWTIIPAIILIFIALPSLQLLYLMDEVNNPFLTIKAIGH
                     QWYWSYEYADYRELEFDSYMIPTSDLSSGMPRLLEVDNRLILPAQTPIRVLVSSADVL
                     HSWAIPSLGVKMDAVPGRLNQVNLFISRCGIFYGQCSEICGANHSFMPIVIETTNFSS
                     FETWVSNFLTE"
                     /product="cytochrome c oxidase subunit II"
                     /transl_except=(pos:7271,aa:TERM)
     tRNA            7272..7343
                     /product="tRNA-Lys"
     gene            7345..7509
                     /db_xref="GeneID:3907687"
                     /gene="ATP8"
     CDS             7345..7509
                     /protein_id="YP_492658.1"
                     /gene="ATP8"
                     /transl_table=9
                     /db_xref="GI:86990339"
                     /db_xref="GeneID:3907687"
                     /codon_start=1
                     /product="ATP synthase F0 subunit 8"
                     /translation="MPQLNLAWWLFNFLISWITLLIVFTALLSTPPIEKPTNVSAQTT
                     SHPLNVWTWN"
     gene            7494..8186
                     /db_xref="GeneID:3907686"
                     /gene="ATP6"
     CDS             7494..8186
                     /protein_id="YP_492659.1"
                     /gene="ATP6"
                     /transl_table=9
                     /db_xref="GI:86990340"
                     /db_xref="GeneID:3907686"
                     /codon_start=1
                     /product="ATP synthase F0 subunit 6"
                     /translation="MNLNLNNIFGQFSPDLVALVPMTLIALVLNLGWLSLTSGTNWLP
                     TRSGALIQAFKRETLKILFQQANPNVAPWIPAFTSVFIFILSVNVLGLLPYAFTSPSH
                     ISLTYSIGIPFWMSVNILGFYLAFNSRLSHLVPQGTPSYWIPLMVIIETISLFAQPIA
                     LGLRLAANLTAGHLLIYLLSTAIWILANSPLIAGVPLSIFFLLFLLEIGVACIQAYVF
                     TALVNSYLAQNL"
     gene            8192..8974
                     /db_xref="GeneID:3907677"
                     /gene="COX3"
     CDS             8192..8974
                     /protein_id="YP_492660.1"
                     /gene="COX3"
                     /transl_table=9
                     /db_xref="GI:86990341"
                     /db_xref="GeneID:3907677"
                     /codon_start=1
                     /product="cytochrome c oxidase subunit III"
                     /translation="MAHQHPYHLVDQSPWPLTGAISALMMTSGLILWFHTNSNSLLIA
                     GTLLLTLTILNWWRDVIREATFQGSHTLPVNTGLRYGMILFITSEICFFFAFFWAFFH
                     SSLAPTIELGVSWPPTGISPINPFLVPLLNTAVLLSSGVTVTWAHHSILAGNRTESIQ
                     ALFLTIALGIYFTALQAWEYYDSPFTIADSVYGSTFFVATGFHGLHVLIGTTFLLICF
                     LRLIFFHFSNNHHFGFEAAAWYWHFVDVVWLFLYVCIYWWGS"
     tRNA            complement(8973..9043)
                     /product="tRNA-Ser"
                     /note="codons recognized: UCN"
     gene            9073..9423
                     /db_xref="GeneID:3907681"
                     /gene="ND3"
     CDS             9073..9423
                     /protein_id="YP_492661.1"
                     /gene="ND3"
                     /transl_table=9
                     /db_xref="GI:86990342"
                     /db_xref="GeneID:3907681"
                     /codon_start=1
                     /translation="MYNFTITLTSILLITGLITAAAHALPNRNIDLEKSSPYECGFDP
                     LNHARIPFSFRFFLVAILFLLFDLEIALLFPFPVSAFFMSPNTSLELAIAFLLILTLG
                     LAFEWSQGGLDWAE"
                     /product="NADH dehydrogenase subunit 3"
                     /transl_except=(pos:9073..9075,aa:Met)
     gene            9431..10813
                     /db_xref="GeneID:3907682"
                     /gene="ND4"
     CDS             9431..10813
                     /protein_id="YP_492662.1"
                     /gene="ND4"
                     /transl_table=9
                     /db_xref="GI:86990343"
                     /db_xref="GeneID:3907682"
                     /codon_start=1
                     /product="NADH dehydrogenase subunit 4"
                     /translation="MIYLILASSSSLILSWAVPRTLLWPSTIICSLIISSLTLNLAQN
                     HIPSLWHNISASFATDPLASPLITLSIWLGPLSLIASINTIKSLPLINQRTFISLIFI
                     ILTALILTFASLELTLFYIAFETTLLPTLILISRWGANKERYQASTYFLFYTLVGSLP
                     LLIAIISIYTVTESSLLPAIFLGNNITSLPTALTSIWWIFCLIAFIIKMPIYGFHLWL
                     PKAHVEAPIAGSMILAAILLKLGGYGLARTITIFIIPASVNISFPLTTFCIWGALITS
                     IICLRQTDLRFFVYSSCPGHLSLVASGIFSISLWGMNGALTLMIAHGLISSALFCLAN
                     LLYERNTTRTLSITRGFKLVTPLLTVWWIITCVTNLGLPPTPNLIGELLIISTIIDWN
                     ILSTPIITTATIFGALYSLLILVNTNNNSFPSFITNARPITTSEHTLMALHLIPLAFI
                     IFNPSHILIN"
     tRNA            10822..10890
                     /product="tRNA-His"
     tRNA            10891..10959
                     /product="tRNA-Ser"
                     /note="codons recognized: AGY"
     gene            10960..12861
                     /db_xref="GeneID:3907684"
                     /gene="ND5"
     CDS             10960..12861
                     /protein_id="YP_492663.1"
                     /gene="ND5"
                     /transl_table=9
                     /db_xref="GI:86990344"
                     /db_xref="GeneID:3907684"
                     /codon_start=1
                     /product="NADH dehydrogenase subunit 5"
                     /translation="MVIEITSIIATINVTIITILFVSIFCLQGTTLPYNSGPNLNFGA
                     LHDNKFEYTHNSSLLFSSVLKSSALLSLIPLFLNVNFNTPETIVSVTEWLPNNAHLIN
                     LELRFDLSFNLFFSVALFVSWSILEFSHYYMAQDPAPNNFFRLLIIFLLNMIILTSTE
                     NVFLLFIGWEGVGFLSFLLISWWTTRASANNSALQAVIYNRIGDIGILLSFSLSVTTF
                     NSWTLSEIFILQPSGSLSNILLVGALIAAAGKSAQFGLHPWLPAAMEGPTPVSALLHS
                     STMVVAGIFLLIRLGPVYSNVNTFNTWCLILGSITAIFAATTAISQHDIKKIIAYSTT
                     SQLGLMMVAIGLNQPEIALFHICTHAFFKAMLFLSSGSIIHSLKDEQDIRKMGGLHLI
                     LPNTTACIILGSLALSGTPFLAGFYSKDLILELGLSNLSNLIGIVLALLATLLTAAYS
                     FRIIHFCFTNSPAFSPLSPTSEENINLTNVLNRLAIGTIISGWLISNFILQPPNITIS
                     LTLKSLAALLTVSGIVLTASLLRTLSLNMPPNNLINANTFTTNQWFYEHASHNILTSL
                     SFSLSLTGSTQSIDRGWSENLGAQGINSASSEISREYQLTQTGYIKQYLLLSTTTFTI
                     IAIVSTTFL"
     gene            complement(12913..13401)
                     /db_xref="GeneID:3907685"
                     /gene="ND6"
     CDS             complement(12913..13401)
                     /protein_id="YP_492664.1"
                     /gene="ND6"
                     /transl_table=9
                     /db_xref="GI:86990345"
                     /db_xref="GeneID:3907685"
                     /codon_start=1
                     /product="NADH dehydrogenase subunit 6"
                     /translation="MVFYAVIVVMPFGSTLVFYSLSPYFGALGLVLVAVSGCFLCGLL
                     GSSFVALVLVLIYMGGMLVVFVYSTAISAERYPAVSNLNEVLLLSGVGVVWAFVSFDP
                     FLSFSLGGWSMTVESDLVGGGALYNALGGYLLVGGFVLFIALVVALVITYGAEYNILK
                     AL"
     gene            13416..14553
                     /db_xref="GeneID:3907678"
                     /gene="CYTB"
     CDS             13416..14553
                     /protein_id="YP_492665.1"
                     /gene="CYTB"
                     /transl_table=9
                     /note="TAA stop codon is completed by the addition of 3'
                     A residues to the mRNA"
                     /db_xref="GI:86990346"
                     /db_xref="GeneID:3907678"
                     /codon_start=1
                     /translation="MTGPLRKSHPLFNVVNNFLIDLPSPSNLSICWNFGSLLGLCLIT
                     QIITGLFLAMQYTSDISLAFSSISHICRDVNYGWLLRNIHANTASFFFLCIYFHIGRG
                     LYYGSYINKEAWNVGVILLLLTMLTAFVGYVLPWGQMSFWGATVITNLVSALPYIGTS
                     IVQWLWGGFSVDNATLTRFFAFHFLFPFIITALSVIHLFFLHQTGSNNPTGIESKFDK
                     TPFHTYFSYKDLTGFVALFTLISAIVLLSPTLLSDPENFNPANPLVTPVHIQPEWYFL
                     FAYAILRSIPNKLGGVIALLASILILFMVPILHTSNNQASTFRPVSQSLFWCLTTIFL
                     FLTWIGSQPVEDPFILLGQIASTAYFLLFLFAIPLTSELENKLIF"
                     /product="cytochrome b"
                     /transl_except=(pos:14553,aa:TERM)
     tRNA            14554..14624
                     /product="tRNA-Phe"
     rRNA            14625..15553
                     /product="s-rRNA"
                     /note="12S ribosomal RNA"
     tRNA            15554..15622
                     /product="tRNA-Glu"
     tRNA            15630..15703
                     /product="tRNA-Thr"
     misc_feature    15704..16234
                     /note="putative control region"
BASE COUNT     5048 a   4538 c   2550 g   4098 t
ORIGIN      
        1 agatagaaac tgacctggct cacgccggtc tgaactcaga tcacgtagga ttttaatggt
       61 cgaacagacc aaccctcagg agctgctgca cccctaggta atcccgatcc aacatcgagg
      121 tcgcaaactt ccttatcaat aagaactctc caagaaaatt acgctgttat ccctacggta
      181 acttattcct ctaatcgccc tttaccggcg gatccccgaa aaagcaacac ctgcatggaa
      241 gttggcactt caccaaatgc ttaataaacg gaggataact attctccgca gttgccccaa
      301 ctaaagctac aagcacataa ccaagccgcc taaacggtaa actcaccccc tttaaaaaag
      361 aaaattagcc cctaggcgac caaaccaact tgtgcaacta actaaagctc gatagggtct
      421 tctcgtccca cgattacacc cccgcttctt cacgaggata tcaaattcaa gatctgggag
      481 ggagacagct gaacctccgt cttgccattc ataccagccc ccattcaaag ggcaaatgat
      541 tatgctacct tcgcacggtc aagataccgc ggccgtttaa ctaagtcacc gggcaggcag
      601 gaccctttat acataagaaa actttacaaa gggcgatgtt tttggtaaac aggcgaagtc
      661 cccacatttg ccgagttcct tcccctcatc tctctaattc ttaccaggcc gcttgagtta
      721 gcagacagac aaaagcgaac tatgctttcc cgcacatata tacttctttc catcaaaaat
      781 taggactgct taatacacaa aaggcctact ctacttcttt actaattcca gcattataac
      841 tcctgcaacc ccgcaggact cccccgtaaa atagtcacaa cataaaaccc gccttacaaa
      901 aatccgtcta cacgccacgg gctacataaa acaagcttta acgccctcgt tcggatagat
      961 gccattaatc ctaccactaa tcgagaccca attaacgtgt ttccctgcgc atttttaacc
     1021 catggctcag gcttttacct ccttgacaag aaagcttatc cctccttgtc tacgctttga
     1081 attcccatta aggatttaat cattatccac gtgataacac aaccttaata gccaaacaaa
     1141 catggctaac accaatttcc ggggaaacca gctatcgttg agcacgataa acatttcaca
     1201 tctaatgtac cctcaaacct tactattgca acagtaaaag ccttctcctc actaggagag
     1261 tacactagct cgctcaaatt cgggtacggc aactctttac caaaatactc accgaaccat
     1321 catacaaaag gtacagggct ttactctttc tttcctactc ttagatattt cacgatattt
     1381 caactttccc tcacggtact acccctttag ctcttactac gagtttcact gataacctac
     1441 tactcctgct tgtcccaaac tatcaatatt ttggtaaact taaaacatca cagttttatt
     1501 attccctcac ccttacaagg ctagtcttta aaaatctaat tattccgtat aaaatctaca
     1561 gcaaagaagc gaacacagga agactcacca gacccagcaa acttaccctt aaacccccgc
     1621 aaagaaccaa accacgaacc gtaacagcac ctgattttcc acccagcagc ccccgccaac
     1681 caaagagaac taaagaatgt tgaggaaaca gtaccaaact ccttttaaag gacacgcgga
     1741 ggtaataaaa caaactaagc aaacttcctg cgactaaaaa gcccctcgcc agaatactac
     1801 ccctctcaag aagacactta agagaaacga actttatcag aaagccaaaa agaggaggca
     1861 aaccccccaa ggaaagcaca cccagcacca tgccggcact ccccccaaga ctaaagtacg
     1921 agagccgacc tacatgggat aaggtcttta aatcaaactc tctcgcaatc aaaaacaccc
     1981 tagaattagt aattacataa accaacaaca taatgcaacc ggcattaaca gaatacccca
     2041 cggtcgaaca gatccacccc atatgtgcta ccgatgaaaa agccaagatc tttcgcacct
     2101 gcgtctgatt caaaccacct cacccaccta tcaacacaga aaggacaccc aaacagacca
     2161 acacccgaat gtctacgcta ttaattacat acaccaagac agaaaaggga gccaacttct
     2221 gtcaagttga caaaaccaaa ccctccagaa agccaacccc ctgaacaaca tctgggaacc
     2281 aatagtgaca tggaaagagc cctaacttaa gccccacggc caaggtaatc agcacggaag
     2341 aaaccctaag taagggttga ccgactagcc acgaggaact aaaccaagct tggataacaa
     2401 caacgttcag tatgacagca gccctcacgg actgtaccaa aaaatacttt accgacgact
     2461 ctacctttcg aggtaaaaac cctccacata aaataggtaa aatagacaaa gtattcacct
     2521 ccaaccccac ccacaaggta aaccagtgat gacttcttaa gacaataaaa gttccaaata
     2581 ccacactaat aaccaacacg ataaaaaccc tacgatgcat aaaacctgga aggagtttaa
     2641 ccttcagcaa cctaattatc agctaggaac ccctacttta gggagcaggt tctataccaa
     2701 aaccaagctg ggaggcaaaa tatcaacgga aaccagcaac accctataaa ataccaacac
     2761 ccccaaactg aagggtaaat acttcttcca agttaaatac atcaaatgat cataccgaaa
     2821 ccgtgggtaa gacgcccgaa cccataaaaa cagaacaacc agaaatacag tcttaaccct
     2881 cactatcaga acccccatag gaaaaacacc cccaaagggg cttgaacccc caaaaaacaa
     2941 gaccaccgaa agaaggttca taaaaattat tttcccgtat tctgctataa agaacatagc
     3001 aaaaggcccc ccagcatatt ctactttata ccctgaaaca atctctgact ccccctccgt
     3061 tagatcaaaa ggagcacgat ttgtctctgc caaagtagaa acaaatcaga ctacaaacaa
     3121 aggtgaacaa caaaagacca accaggaacc tccctgactt ttttcaatca ccctaaggct
     3181 aaagcctccc gaaaatacca ccacccctaa caaaatcagc cctagactta tctcgtaaga
     3241 gaccgtttga gcaacagccc gaacagctcc taaaaaggaa taatttgaat tagatgccca
     3301 acccgaccct aacaaagcat aaacagatag cctagacaac cccatcacca aaacgagcga
     3361 tagtttaact tccagcacac aaaaaccaac tggaataagt gaccacaaaa aaagcgcaat
     3421 ccttaaaaag aggatggggg acaaaaaaaa caaataaggc gaagctttag aaggctttaa
     3481 agtctccttt ataagcaact tgaacccgtc tgctaaaggt tgcaacagac caaacggccc
     3541 cactacatta ggccccttac gaaactgcat ataaccaaga accttccgct ctactaaagt
     3601 taacaaagcc actgctaaca acaccggaat tataaaaaca actgatttaa caataaaaac
     3661 taacccatcc acaactaaag aaaggacttg aaccttcgat agagaaacct tagatttctt
     3721 gcattaccgc tttgctactt tagctatttc tatatataag aattatctga catgcttcac
     3781 ccctgattgc aagcagggac cccttagttg gaagccaaga atactgatgt actcgtgaaa
     3841 cctggcgaga gaaggactca aaccctcctt attggattta caatccacta cattaacctc
     3901 tgccatctcg ccaaagggct agttaaactg ataacaccag aatgtcagac tggaattgct
     3961 ggctaataat ccagcgctct ttgaaaataa agggaggtat ctatccttcc atttttgagg
     4021 tatgaaccca aaagcttcta ttagcttact ttacttacta ttttcctagg gtagagcttg
     4081 accaagcatc tcttttacac ggagaagata tctgtgcaaa ccagattacc ttgaaagttc
     4141 tggcggatat tacccgcgtc tatagatttg caatctaaaa tgttaattac actacaaaac
     4201 ccaggggtta aaaacctctc atttttattt aaagctttga aggctattag ttttaattaa
     4261 cttaaacccc ttattagtga atttagttta acaaaaacat ttgacttgca cttaaaaact
     4321 ctaagtttaa accttagaat tcacaagcta ggagaaggac tcgaaccttc gatattagat
     4381 cctaaatcta gcgcagtaac cactttgcta ccctaacctg agtcgacaag tattgatctt
     4441 gttatctcct ggttaacggc caattgcctt tccattaggc tacgacccaa atagaaagta
     4501 gtttaatagg taaaacaaag aattttgatt tcttcaacat aagttcaacc cttatctttc
     4561 tagtcagaaa aataggactc tacacctata ccagcaactc ccaaagctac cattcttgac
     4621 taaactattt tctgtttaac ctatatataa tgaaattata aaccatgcaa ctaaggcgat
     4681 gatttttttc aacaaaacac aagggcatcg ggacactata tctaatattt ggggcctgag
     4741 caggaatggt tggaacagcc atgagagtaa taatacgaac agaactagcc caaccaggct
     4801 cactcctcca agacgaccaa atatacaacg taatagttac agctcacgct ttagtaatga
     4861 tattcttcat ggtaatgcca attatgatcg gaggattcag taactgactg atccctctaa
     4921 tgatcggagc acccgatatg gccttccccc gaatgaacaa catgagcttt tgactagtac
     4981 ccccctcttt tctactactc ctagcatcag ccggagtaga aagaggcgct ggaaccggat
     5041 gaaccatcta ccctccatta tctagcggcc tagcccacgc cggaggatca gtggaccttg
     5101 caatattctc actccacctt gcaggagcat cctctatcct ggcctccata aaattcatca
     5161 ctactgtaat aaacatgcgg accccaggaa tctcgttcga ccgtctacca ctattcgtct
     5221 gatcagtatt cgtaacagca tttctgctac tcctttccct tcccgttcta gctggagcta
     5281 taacaatgct tctcaccgac cgaaacgtaa acacaacctt ctttgacccc gcggggggag
     5341 gagaccctat tttattccag caccttttct gattctttgg gcatccagag gtgtacattc
     5401 ttatacttcc aggatttgga atgatatccc acgtaatcgc tcactactca ggtaagagag
     5461 aaccttttgg ctacctaggt atggtctacg ctattgtgtc tattgggatt ttagggtttc
     5521 tagtgtgagc tcaccacatg tttacagtcg gtatggacgt agacactcgg gcatacttca
     5581 cagctgcaac aatgataata gccgtaccca caggaatcaa ggtcttcagg tgaatggcaa
     5641 cgctacaagg caggaacctc cgatgagata caccactgct ttgagcccta ggatttgtat
     5701 tcttatttac cattggggga ctgacaggcg taatcctggc aaaatcatcc atcgatgtca
     5761 tcctccacga cacctattac gtagtcgccc acttccacta tgtcctatca atgggtgcag
     5821 tgtttgctat tttcgcagga ttcacacact gattccctct cttttctgga gtaggactac
     5881 accccctatg ggggaagatc cacttcgcat taatgttcat aggagtaaac ctcacctttt
     5941 tcccccaaca cttcctagga ttagcaggta tgccacgacg atactccgac tacccggacg
     6001 cctataccct ttggaatact atctcatcca taggcagcac catatccctc gtagcaacac
     6061 tgatattcct atttatcatt tgggaagcct tcacttccca gcgaaccact gttcgacccg
     6121 aattcgcacc ctcctcacta gaatgacaat actcttcctt tcccccctcc catcacacct
     6181 tcgacgaaat tccggcaacc gtatacttaa ttaagtatga ggattagttt aacaaaaaca
     6241 tttgacttcg actcaaaaaa cttcagttac accctgaaat ccttttatta cacctatctt
     6301 tattagcacc atatccatat actacctagg attactaggt atattaatta atcggctaca
     6361 cttcttgtct atcctcctct gccttgaact tctcctaata tcgctgttcc taagaatgac
     6421 aatatgggca ctaaaaaccg gaaccaacct cttcgtagcg aaaaacctta tccttcttac
     6481 tctttctgcc tgcgaagcaa gggccggcct ttcccttatg gtagcacttt cacgaactca
     6541 caaatcagac ttagtcatag cactgaatat cttacaacaa taaatggcaa attgaaccca
     6601 actaggatta caagacgcat cttcccccct aatggaagaa ctaatctatt ttcatgatta
     6661 cactctaatc attcttaccc taatcacaat actagtcttc tacgggttag catcactcct
     6721 attctcctcc agaacaaacc ggttcttttt agaggggcaa ggactagaaa ccatatgaac
     6781 aatcattccc gctattatcc ttatattcat cgcacttccc tccctccagc tcctctacct
     6841 catggacgag gtaaaaaacc ccttcctcac cataaaggcg ataggacacc aatgatactg
     6901 gagatacgaa tacgcagact accgtgaatt agaatttgat tcatacatga ttcccacttc
     6961 agacctttcc tctggtatgc cccgcttact agaagtggat aaacgactga tactccccgc
     7021 ccaaacgcca atccgagtat tggtatcctc tgcagacgtc ctccactcct gggcgatccc
     7081 ttccctcgga gtaaagatgg atgcggtccc aggacgacta aaccaagtga aattgttcat
     7141 ttcccggtgc ggcatattct atggtcaatg ctcagagatt tgcggggcaa accatagatt
     7201 catgcccata gtcattgaga ccacaaaatt ttcctcattc gaaacatgag tatctaactt
     7261 cttaacggaa tctctggtaa gctaatacgg aagcatcaaa ctcttgactt gaataaaagt
     7321 ggaagtccac ccactaccag agagatgcca caactaaatc tagcctgatg attgtttaaa
     7381 ttcttaatta gatgaataac attacttata gtcttcactg ctttgcttag cacacctcca
     7441 atagaaaagc cgactaaagt cagagcccaa accacctcac accccttaaa agtatgaacc
     7501 tgaaactaaa aaacatattc ggccaattct ccccagacct cgtagctctg gtccccatga
     7561 ccctgatcgc cttagtcctc aacctagggt gactctcttt aacaagagga acaaactgac
     7621 tccccactcg aaggggcgct ttaatccaag cctttaagcg agaaactctg aagatactgt
     7681 tccagcaagc caaccccaaa gttgcgccct gaatcccagc ttttacctct gtatttatct
     7741 tcatcttgtc agtaaaagta ttaggactac taccgtatgc cttcacctca ccaagccaca
     7801 tatcacttac ttattctata ggcatcccct tctgaatgtc agtaaatatc cttggattct
     7861 atctagcgtt caaaagtcga ctaagacacc tagtacctca aggtaccccc tcctactgga
     7921 tccctctaat ggtaataata gaaacaatca gactatttgc acaacccatt gcattgggct
     7981 tgcgattagc cgccaaccta acagcagggc accttcttat ttacctcctc tctacagcaa
     8041 tttgaatctt agcaaaatcc ccccttatag ccggagtacc cctctcaata tttttcctcc
     8101 tcttccttct ggaaatagga gtagcctgta ttcaagccta cgtgttcact gcactagtta
     8161 aatcctacct tgcccaaaac ctataaaaat tatggcccat caacacccct accacctagt
     8221 agaccaaaga ccctgacccc tcaccggggc tattagcgct ctcatgatga cttccggtct
     8281 aatactatga ttccacacaa aaagaaactc actacttatt gcagggactc tgctccttac
     8341 cctaactatc ctaaaatgat ggcgagacgt aatacgagaa gcaacatttc aaggcagaca
     8401 caccctaccg gttaacaccg ggctgcgata cggaatgata ctttttatta cctcggagat
     8461 ttgctttttc ttcgctttct tctgagcatt cttccacagc agcctagcac caaccattga
     8521 gctaggtgta tcctgacccc caactggaat tagtccaatc aacccctttc tggttcctct
     8581 cctcaacacc gccgtcctac tctcatccgg ggtaacagtc acttgagccc accacagcat
     8641 tctagccgga aaccgcacag aatccataca agccctattt ctaacaatag ccctgggtat
     8701 atatttcacc gccctgcaag cctgagaata ctacgactca ccatttacca tagccgacag
     8761 agtatatggc tctacatttt ttgtggccac cggcttccac ggacttcacg tactcatagg
     8821 aacaactttc ctcttaatat gcttcttacg attaatattc ttccactttt ccaacaacca
     8881 ccactttggc ttcgaggcgg ctgcctgata ctgacacttc gtagacgtag tctgactatt
     8941 tctatacgtt tgcatctatt gatgaggatc ctaagagaag aaaggactcg aacctttatc
     9001 tttctagttt caagctaaac gcatcccact ctgccacttc tcccccaaat aattcttata
     9061 taccaaataa aaatttacaa atttactatc actctaacat caatcctcct gataacagga
     9121 ttaatcactg ccgcggctca cgctctaccc aaccgaaaaa tagacctcga aaagtcctcg
     9181 ccctacgaat gtgggtttga ccccttaaaa cacgcacgca taccattctc ttttcggttt
     9241 ttcctagttg ctatcttatt cctcctattc gacctggaaa ttgccctatt attcccgttc
     9301 cccgtaaggg cattttttat gtccccaaac acctcgctag aactggctat agcattctta
     9361 ctaatactta cacttgggct agccttcgag tggtcccaag gaggtctcga ctgagctgaa
     9421 taataaacta atgatatatc ttatcttggc ctcctcgtca agcctgatcc tatcttgggc
     9481 cgtcccccga acacttctat gaccctcaac cataatttgt tcactcatca tctccagact
     9541 aactcttaac ctagcccaaa aacacatacc ttcattatga cacaaaatct ccgctagctt
     9601 cgctaccgac cctctagctt cacctctaat aaccctgagc atatggcttg gccctttatc
     9661 cctcatagcc agaataaaaa caataaagag cctaccacta ataaaacagc gcactttcat
     9721 ttcccttata tttatcatac tgactgccct aatccttaca tttgcctcgc ttgaattaac
     9781 cctattctac atcgcatttg aaacgaccct tcttccaaca ctaattctca tatcccgctg
     9841 aggggcaaaa aaggaacggt atcaagctag cacatacttc cttttttata ctctcgtagg
     9901 ttccctaccc ctcctcatag ccatcataag catctacacc gtaaccgaat catctttact
     9961 accagccatt ttccttggaa aaaaaataac atcactcccc actgcattaa cctccatatg
    10021 atgaatcttc tgccttatag ccttcataat aaagatgccg atttatggat tccacctgtg
    10081 actccctaag gctcacgtag aagcccccat agctgggtca atgattcttg cagccatcct
    10141 cctgaagctc gggggatacg gcctcgcccg aaccatcaca atatttatta tacccgcttc
    10201 cgtaaaaata tcattcccac tcacaacctt ctgcatatga ggcgctctaa taacaaggat
    10261 catttgccta cgacaaacag acctgcggtt cttcgtctat tcatcttgtc cgggccacct
    10321 gagattagta gcttctggca tattctcaat atccctctga gggatgaaag gcgctcttac
    10381 tctcatgatc gctcatggat taatatcctc agccctgttt tgtcttgcaa aactcctcta
    10441 tgaacgaaac accactcgaa ccctttcaat aacccgaggc ttcaagctgg ttaccccact
    10501 acttactgta tgatgaataa taacatgtgt aacaaacctg ggactacccc ctactcccaa
    10561 cctaattggg gaacttctca ttatatctac cattatagac tggaaaatct tatctacacc
    10621 cataatcact acagcaacaa tatttggggc cttatactcc ctcctaatac tagttaacac
    10681 taacaaaaac tccttcccaa gttttattac aaaagctcgc ccgataacca cttcggaaca
    10741 caccctaatg gctctccacc tcatccccct agcatttata atattcaacc cctcccacat
    10801 actaataaaa taaccccaat gactaaagta gtttaataaa aacgctaatt tgtggtatta
    10861 gaatcaccag ttaaaacctg gtctatagtc cgaaacttat tggcttattc tagtcctgct
    10921 aagtccaaga atctgtagtt caattctata gaagtttcga tggtaataga aatcacgaga
    10981 ataattgcaa ccataaaagt caccattata accatactat ttgtctccat attttgcctc
    11041 cagggaacta cattgcccta taaaagaggc cctaacctta actttggagc acttcatgat
    11101 aaaaagttcg aatacacaca caaaagaagg ctattatttt catctgtact aaagagatca
    11161 gccctcctct cactcatacc gctcttcctg aaagtaaaat tcaaaacccc agagacaata
    11221 gtctccgtaa ccgaatgact tcccaaaaac gcacatctca ttaacctcga actacgattc
    11281 gacctttcat tcaaactatt cttttcagtt gcactattcg tctcctgatc aatcctagag
    11341 ttctcacact actatatggc acaagaccca gcaccgaaca aattcttccg cctcctaata
    11401 attttcctac taaaaatgat catactcacc tccactgaaa acgtattcct tttatttata
    11461 ggctgggaag gagtcggatt cttatcattc ttattaataa gatgatgaac tacacgagca
    11521 agagcaaaaa aatctgccct tcaggcagta atctacaacc gaataggaga cataggtata
    11581 ctcctatctt tctccctcag ggttacaacc tttaactcct gaactttatc ggaaatattt
    11641 atcctacagc ccaggggctc tctcaggaat attctgctag ttggagccct catagctgcc
    11701 gcgggaaagt ccgcccaatt cggtttacac ccctgactcc cagcagcaat ggaagggccc
    11761 acccctgtat cagccctcct ccacagctct acaatggtag tagcaggaat attccttcta
    11821 atccgccttg gtcctgtata ctcaaacgta aaaaccttta aaacgtgatg ccttatacta
    11881 ggctccatca cggccatatt tgctgcaaca accgcaatct ctcaacacga cataaagaag
    11941 ataatagcat actccactac caggcaacta gggctcatga tggtagccat aggcctaaac
    12001 caaccagaaa ttgcactatt ccatatttgc acacacgcat tcttcaaggc aatgctgttc
    12061 ctatcctctg gtagaatcat ccacagacta aaggacgaac aagacatacg aaagatgggc
    12121 gggctccacc taatactccc caacacaacc gcttgtatta tcctgggaag acttgcctta
    12181 tctggtacac cattcctggc cggattttac tccaaggacc taatattaga attaggcctc
    12241 tctaaacttt cgaacctgat aggaattgtt ttggcccttc tagcaaccct cctaaccgcg
    12301 gcatactcat tccgcatcat acacttctgc ttcaccaaaa gaccagcctt ctcacccctt
    12361 tctcctacca gagaagaaaa aatcaaacta accaaagtgt taaaacgact agctattggt
    12421 acaataatct caggatggtt aatatcaaac tttatcctac agcccccgaa aatcaccatc
    12481 agactcaccc ttaagagcct cgctgcccta ttaactgttt ccggaatagt attaacagca
    12541 tcactacttc gcactctttc cctaaaaatg ccccccaaaa acctcataaa cgccaaaaca
    12601 ttcaccacaa aacagtgatt ttacgaacac gcatcccaca acatcctcac gagcttatct
    12661 ttctcgctct ctttaacagg aagaacccaa aggatagacc gaggatgaag agaaaatcta
    12721 ggcgcacaag gaataaactc ggcctcttct gaaatttccc gggagtacca actaacccaa
    12781 acaggctata ttaagcagta ccttctcctc tctaccacca ctttcaccat tatagccata
    12841 gtctccacca cctttctata ataaccaaca ccgcactctg tacactcata acaactgaac
    12901 acaaacctaa ccctacaggg cctttaatat tttatattcc gccccataag taatcactag
    12961 cgcaaccact agagcaataa aaagtacgaa cccccctacc aacaagtagc cccccaacgc
    13021 tttatataaa gccccacccc ccacaagatc cctctctact gtcatagacc accccccaag
    13081 cgagaagctc aagaaaggat caaacctcac gaaagcccaa acgacaccta caccccttaa
    13141 gaggagtacc tcattcaggt tgctcactgc cgggtaccgc tccgcagata tagccgtaga
    13201 ataaacaaaa acaaccaaca ttccccccat ataaataaga acaagcacca aggccacaaa
    13261 ggaagatcct aggagcccac aaagaaagca ccccgacacg gccactaaga ccaaacctag
    13321 agcaccaaaa taaggagata acctataaaa caccagagta cttccaaagg gcataacaac
    13381 tatcacagca taaaaaacca ttatatataa aaattatgac aggccctctc cgaaagagac
    13441 accccttatt taaagtagta aaaaatttcc taatagacct cccctcccct aggaaactgt
    13501 ccatatgttg aaaattcggg tccctattag gcctttgcct gatcacccaa ataatcacag
    13561 gcctatttct cgctatgcaa tatacctcag atatatctct agccttttcg tccatcagcc
    13621 acatatgccg agacgtaaac tatggttgac tcctacgaaa tatacacgcc aaaacggcct
    13681 ccttcttttt cctttgcatt tatttccaca taggccgagg attatactac ggctcctaca
    13741 taaaaaagga ggcctgaaaa gtaggcgtta tcctccttct cctcaccatg ctaacagctt
    13801 tcgttgggta cgttctccca tgaggccaaa tgtcattttg aggagcaaca gtgatcacaa
    13861 accttgtatc tgccctcccc tatataggaa catcaatagt ccaatggctt tgaggaggat
    13921 tctcagttga caacgccacc ctcacccgat tttttgcctt ccatttccta tttcccttca
    13981 tcatcaccgc tctctcggtc atccacctat tcttcctcca ccaaactggt tctaacaaac
    14041 ctacgggaat agaatcaaag tttgataaga cccccttcca cacctacttt tcctataagg
    14101 acctcacggg gtttgtagct ctatttaccc tgataagcgc aatagttctt ttatccccaa
    14161 ccttacttag agaccccgaa aaattcaaac ccgctaaccc tttagttaca ccagttcaca
    14221 tccaaccgga atgatacttc cttttcgcct acgcgatcct ccgatccatc cccaaaaagt
    14281 taggaggcgt aatagcctta ttagcatcaa tcctcatctt gttcatggtc ccaatcctcc
    14341 acacatcaaa caaccaagct agcacctttc gacctgtttc acaaagactc ttctgatgtc
    14401 ttaccaccat cttcctgttc ctaacatgaa taggaaggca acccgtagaa gacccattca
    14461 tcctcctcgg gcaaatagcc tcaacggctt acttcctctt gttcttgttc gcgattcctc
    14521 taacatcaga actagagaaa aagctgattt tctgcaaaga tagcttaaca gaaaagcaaa
    14581 gcactgaaaa cgcttaaata aaggttcgag tccttttctt agcaaccgat ttggtcctag
    14641 tccttccctc aactttctcc aggatgatac atgcaaaccc ctaagttcta cggtgagctc
    14701 aatctgcttc tggcctcttc caagacacca ggacactaaa aatagcatca ggcaccattc
    14761 ctcgtagccc aagacgctaa ggcctaccca aacaaagata gcccacacct gcaagtactt
    14821 gacattacac aataagcgct agcttgatgc agccgtagag aaaaaaaccg gtaaattatg
    14881 tgccagccac cgcggttata cataagattt tagttgaggg cctcggtaaa aaggtgataa
    14941 aaatgcacca gagtcctcgc cccctcaagc agtaataagc taacaggacc ctaagaacta
    15001 ttccaccaaa ccctgcccta cccaaaccct tgatatttat caccaaagct caaagataaa
    15061 ctgggattag ataccccatt atatgagccc taaaacaacc taaacacctg agaactacga
    15121 acaagagttt aaaactcaaa ggacttggcg gttttccaga cctccttgga ggagcttgct
    15181 atctaaccga taacccacga aatacctcac cagcctttgc aaaccgcagc ctgtatacca
    15241 tcgtcgtcag tctacccttt aaagacagta tactgaatgg agtaaattgt tatatctcct
    15301 ctacgtcaga tcgaggtgca gctcataagc tggggataag tgagctacaa taactaacta
    15361 acaggccctc taaaccaaga tatggacaag cccatgaaaa ccgggactca aaacaggatt
    15421 cagcagtaac gcctaacaga gaataggtgt gaagcacaca gctctggaat gcgcacacat
    15481 cgcccgtcac tctcgtccac agaggagaaa agtcgtaaca aagtaggcgt attggaaaat
    15541 gcgcctggta caaattctta tagttgaacc acaacagcag cttttcacgc tacaagcttg
    15601 ggttagaccc ccaatgagaa ttgcacaagc gcctcaaaag ctgacgggta agcaattaat
    15661 cttgtaaatt aaaaggcgaa ggttcgagtc ctttttgagg cttcccataa cccccccccc
    15721 ctccgggggg ggggttagct gggtataagt ttgtgttctt gagaaagcta tacagggcca
    15781 aggtattatg caaacctccc ctatggggta atacaatacg gaaagataca ccttttttct
    15841 tacttttccg ctccgcgggg ggatagttag ggtaaggcta cataggctaa acccagttta
    15901 tacgccatcc tacactctag ttataagttc tttctgatac aggattaata ctaaacaatg
    15961 acagtacccg ctttaccgtc ttatcaaaaa accacggtca cgtaggccct atgcaactat
    16021 ataactatcg acgtcacact ttaacccagt ttttaaaccc taaacctctc acgcagaggc
    16081 ttgacgtttc cactgcctga agctaccgca accgcagaca ccaagaacca atctttattt
    16141 tacaacagaa ccttcaaaag tgtttacctt aagatattga caccacccct tcgatccttt
    16201 cgtactagaa gggacccttg ctctattcaa tcgt
//
