Tanzer & Stadler: mir17 cluster (Supplement)

Alignment-scores of stRNAs

The table below lists the mean pairwise identities (% in bold) and the similarity scores of multiple alignments of stRNAs separately for the 5' and 3' arms. The arm containing the miRNA is shown in yellow.

mir17/106 mir18 mir19 mir20/93 mir92/25

miRNAs 5' and 3' 5' 3' 5' 3'

5' arm 70.5 (46.5) 84.3 (35.6) 64.7 (15.7) 75.0 (33.3) 54.0 (6.2)

3' arm 65.7 (32.6) 83.5 (38.9) 73.8 (34.0) 67.8 (18.2) 70.8 (23.3)

# of miRNAs 20 18 30 21 26

	mir17/106	mir18	mir19	mir20/93	mir92/25
miRNAs	5' and 3'	5'	3'	5'	3'
5' arm	70.5 (46.5)	84.3 (35.6)	64.7 (15.7)	75.0 (33.3)	54.0 (6.2)
3' arm	65.7 (32.6)	83.5 (38.9)	73.8 (34.0)	67.8 (18.2)	70.8 (23.3)
# of miRNAs	20	18	30	21	26

Differences in sequence similarity between the 3' and 5' arms are noticable for the miRNA precursors with the exception of mir18. Even for the mir92/25 group the differences are not dramatic, however.