ACGUCACCGCCCGCGGCGCUUCCGGGGGCGCCGCG___GGCGAUGACGUAGAG_GGACGUGCCCUCUAUAUGAGGUUGGGGAGCGGCUGAGUCGGCCUUUU___CCGCCCGCUCCCCCCU__CCCCCCGAGCGCCGCUCCGGCUGCACCGCGCUCGCUCCGAGCUCCGGGCUCCUGCCAAGCUAGCGCCGCCG___UCG_CUCCCUCCAGCCGCCAUCA
......................(((.(((((.(((...((((.....((((...((.((.((.(((.....((((..((((((((((.(((........))...).))).))))))))))..).....))).)))).))...))))....)))))))...........((((.......)))).))))).)))..........................
 minimum free energy = -47.39 kcal/mol (-49.61 +   2.22)