>gi|27065049|pdb|1H2N|A Chain A, Factor Inhibiting Hif-1 Alpha
gi|27065046|pdb|1H2M|A Chain A, Factor Inhibiting Hif-1 Alpha In Complex With Hif-1 Alpha
Fragment Peptide
gi|27065042|pdb|1H2L|A Chain A, Factor Inhibiting Hif-1 Alpha In Complex With Hif-1 Alpha
Fragment Peptide
gi|27065036|pdb|1H2K|A Chain A, Factor Inhibiting Hif-1 Alpha In Complex With Hif-1 Alpha
Fragment Peptide
Length = 349
Score = 32.7 bits (73), Expect = 0.084
Identities = 36/123 (29%), Positives = 51/123 (41%), Gaps = 15/123 (12%)
Query: 113 WIEKLKAELRLPAGTSSKAIVYAAKNGGGFKAHFDAYTNLIFQIQGEKTWKLAKNENVSN 172
WI K + + TS+ ++ G AH+D N QI+G K L
Sbjct: 169 WINKQQGKRGWGQLTSNLLLI--GMEGNVTPAHYDEQQNFFAQIKGYKRCILFP------ 220
Query: 173 PMQHYDLSEAP-YYPDDLQSYWKGDPPK-EDLPDAEIVN-----LTPGTMLYLPRGLWHS 225
P Q L P ++P D QS D P E P+ + V + PG +LY+P WH
Sbjct: 221 PDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHH 280
Query: 226 TKS 228
+S
Sbjct: 281 IES 283
>gi|33357073|pdb|1IZ3|A Chain A, Dimeric Structure Of Fih (Factor Inhibiting Hif)
Length = 349
Score = 32.7 bits (73), Expect = 0.084
Identities = 36/123 (29%), Positives = 51/123 (41%), Gaps = 15/123 (12%)
Query: 113 WIEKLKAELRLPAGTSSKAIVYAAKNGGGFKAHFDAYTNLIFQIQGEKTWKLAKNENVSN 172
WI K + + TS+ ++ G AH+D N QI+G K L
Sbjct: 169 WINKQQGKRGWGQLTSNLLLI--GXEGNVTPAHYDEQQNFFAQIKGYKRCILFP------ 220
Query: 173 PMQHYDLSEAP-YYPDDLQSYWKGDPPK-EDLPDAEIVN-----LTPGTMLYLPRGLWHS 225
P Q L P ++P D QS D P E P+ + V + PG +LY+P WH
Sbjct: 221 PDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPXYWWHH 280
Query: 226 TKS 228
+S
Sbjct: 281 IES 283
>gi|27065812|pdb|1MZF|A Chain A, Human Factor Inhibiting Hif (Fih1) In Complex With 2-
Oxoglutarate
gi|27065810|pdb|1MZE|A Chain A, Human Factor Inhibiting Hif (Fih1)
Length = 351
Score = 32.7 bits (73), Expect = 0.084
Identities = 36/123 (29%), Positives = 51/123 (41%), Gaps = 15/123 (12%)
Query: 113 WIEKLKAELRLPAGTSSKAIVYAAKNGGGFKAHFDAYTNLIFQIQGEKTWKLAKNENVSN 172
WI K + + TS+ ++ G AH+D N QI+G K L
Sbjct: 171 WINKQQGKRGWGQLTSNLLLI--GMEGNVTPAHYDEQQNFFAQIKGYKRCILFP------ 222
Query: 173 PMQHYDLSEAP-YYPDDLQSYWKGDPPK-EDLPDAEIVN-----LTPGTMLYLPRGLWHS 225
P Q L P ++P D QS D P E P+ + V + PG +LY+P WH
Sbjct: 223 PDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHH 282
Query: 226 TKS 228
+S
Sbjct: 283 IES 285
>gi|42543131|pdb|1NRF|A Chain A, C-Terminal Domain Of The Bacillus Licheniformis Blar
Penicillin-Receptor
Length = 262
Score = 30.8 bits (68), Expect = 0.32
Identities = 22/81 (27%), Positives = 37/81 (45%), Gaps = 3/81 (3%)
Query: 83 VSPAEALEWYEKGAALEFDFTDLFIPQVRRWIEKLKAELRLPAGTSSKAIVYAAKNGGGF 142
+SP E + +K EFDF I V+ I ++ R+ +G + +++ + G F
Sbjct: 156 ISPLEQVNILKKFYDNEFDFKQSNIETVKDSIRLEESNGRVLSGKTGTSVINGELHAGWF 215
Query: 143 KAHFDAYTNLIF---QIQGEK 160
+ + N F IQGEK
Sbjct: 216 IGYVETADNTFFFAVHIQGEK 236
>gi|27574087|pdb|1N63|E Chain E, Crystal Structure Of The Cu,Mo-Co Dehydrogenase (Codh);
Carbon Monoxide Reduced State
gi|27574084|pdb|1N63|B Chain B, Crystal Structure Of The Cu,Mo-Co Dehydrogenase (Codh);
Carbon Monoxide Reduced State
gi|27574081|pdb|1N62|E Chain E, Crystal Structure Of The Mo,Cu-Co Dehydrogenase (Codh), N-
Butylisocyanide-Bound State
gi|27574078|pdb|1N62|B Chain B, Crystal Structure Of The Mo,Cu-Co Dehydrogenase (Codh), N-
Butylisocyanide-Bound State
gi|27574075|pdb|1N61|E Chain E, Crystal Structure Of The Cu,Mo-Co Dehydrogenase (Codh);
Dithionite Reduced State
gi|27574072|pdb|1N61|B Chain B, Crystal Structure Of The Cu,Mo-Co Dehydrogenase (Codh);
Dithionite Reduced State
gi|27574069|pdb|1N60|E Chain E, Crystal Structure Of The Cu,Mo-Co Dehydrogenase (Codh);
Cyanide-Inactivated Form
gi|27574066|pdb|1N60|B Chain B, Crystal Structure Of The Cu,Mo-Co Dehydrogenase (Codh);
Cyanide-Inactivated Form
gi|27574059|pdb|1N5W|E Chain E, Crystal Structure Of The Cu,Mo-Co Dehydrogenase (Codh);
Oxidized Form
gi|27574056|pdb|1N5W|B Chain B, Crystal Structure Of The Cu,Mo-Co Dehydrogenase (Codh);
Oxidized Form
Length = 809
Score = 29.3 bits (64), Expect = 0.93
Identities = 14/48 (29%), Positives = 25/48 (52%), Gaps = 4/48 (8%)
Query: 61 NPVMVVGDAVIEESEGITDRFLVSPAEALEWYEKGAALEFDFTDLFIP 108
NP+++ G G+T+ F V+ + + + E+G L F D F+P
Sbjct: 691 NPMIIEGQV----HGGLTEAFAVAMGQEIRYDEQGNVLGASFMDFFLP 734
>gi|51247136|pdb|1OKZ|A Chain A, Structure Of Human Pdk1 Kinase Domain In Complex With
Ucn-01
gi|51247135|pdb|1OKY|A Chain A, Structure Of Human Pdk1 Kinase Domain In Complex With
Staurosporine
gi|47169287|pdb|1UU8|A Chain A, Structure Of Human Pdk1 Kinase Domain In Complex With
Bim-1
gi|47169286|pdb|1UU7|A Chain A, Structure Of Human Pdk1 Kinase Domain In Complex With
Bim-2
gi|47169285|pdb|1UU3|A Chain A, Structure Of Human Pdk1 Kinase Domain In Complex With
Ly333531
Length = 310
Score = 27.3 bits (59), Expect = 3.5
Identities = 11/26 (42%), Positives = 17/26 (65%)
Query: 92 YEKGAALEFDFTDLFIPQVRRWIEKL 117
++K LE+DF + F P+ R +EKL
Sbjct: 241 FQKIIKLEYDFPEKFFPKARDLVEKL 266
>gi|47169307|pdb|1UVR|A Chain A, Structure Of Human Pdk1 Kinase Domain In Complex With
Bim-8
gi|34811348|pdb|1H1W|A Chain A, High Resolution Crystal Structure Of The Human Pdk1
Catalytic Domain
Length = 289
Score = 27.3 bits (59), Expect = 3.5
Identities = 11/26 (42%), Positives = 17/26 (65%)
Query: 92 YEKGAALEFDFTDLFIPQVRRWIEKL 117
++K LE+DF + F P+ R +EKL
Sbjct: 221 FQKIIKLEYDFPEKFFPKARDLVEKL 246
>gi|47169288|pdb|1UU9|A Chain A, Structure Of Human Pdk1 Kinase Domain In Complex With
Bim-3
Length = 286
Score = 27.3 bits (59), Expect = 3.5
Identities = 11/26 (42%), Positives = 17/26 (65%)
Query: 92 YEKGAALEFDFTDLFIPQVRRWIEKL 117
++K LE+DF + F P+ R +EKL
Sbjct: 220 FQKIIKLEYDFPEKFFPKARDLVEKL 245
>gi|50513707|pdb|1T5L|B Chain B, Crystal Structure Of The Dna Repair Protein Uvrb Point
Mutant Y96a Revealing A Novel Fold For Domain 2
gi|50513706|pdb|1T5L|A Chain A, Crystal Structure Of The Dna Repair Protein Uvrb Point
Mutant Y96a Revealing A Novel Fold For Domain 2
Length = 658
Score = 26.9 bits (58), Expect = 4.6
Identities = 17/72 (23%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Query: 45 GFEKVRTLENVLAIYNNPVMVVGDAVIEESEGITDRFLVSPAEALEWYEKGAALEFDFTD 104
G K T+ NV+A N P +V+ + ++ P A+E++ + ++ +
Sbjct: 42 GTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFV--SYYDYAQPE 99
Query: 105 LFIPQVRRWIEK 116
++PQ +IEK
Sbjct: 100 AYVPQTDTYIEK 111
>gi|13096236|pdb|1EE0|B Chain B, 2-Pyrone Synthase Complexed With Acetoacetyl-Coa
gi|13096235|pdb|1EE0|A Chain A, 2-Pyrone Synthase Complexed With Acetoacetyl-Coa
gi|10835613|pdb|1QLV|B Chain B, Pyrone Synthase (Pys) From Gerbera Hybrida
gi|10835612|pdb|1QLV|A Chain A, Pyrone Synthase (Pys) From Gerbera Hybrida
Length = 402
Score = 26.9 bits (58), Expect = 4.6
Identities = 18/70 (25%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query: 6 ESVLESIISPVTMSEFLEEYWPVKP--LVARGEVERFTSIPGFEKVRTLENVLAIYNNPV 63
E+ E +SP+ ++++ +W V P +VER ++ +K+R +VL+ Y N +
Sbjct: 285 ENAAEKALSPLGITDWNSVFWMVHPGGRAILDQVERKLNLKE-DKLRASRHVLSEYGNLI 343
Query: 64 MVVGDAVIEE 73
+I+E
Sbjct: 344 SACVLFIIDE 353
>gi|6730157|pdb|1C5G|A Chain A, Plasminogen Activator Inhibitor-1
Length = 402
Score = 26.6 bits (57), Expect = 6.0
Identities = 15/52 (28%), Positives = 25/52 (48%), Gaps = 7/52 (13%)
Query: 176 HYDLSEAPYYPDDLQSYWKGDPPKE-------DLPDAEIVNLTPGTMLYLPR 220
+YD+ E PY+ D L + KE ++ A++++ G M LPR
Sbjct: 243 YYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPR 294
>gi|49259007|pdb|1SIW|B Chain B, Crystal Structure Of The Apomolybdo-Narghi
gi|46015401|pdb|1R27|D Chain D, Crystal Structure Of Nargh Complex
gi|46015399|pdb|1R27|B Chain B, Crystal Structure Of Nargh Complex
gi|37927741|pdb|1Q16|B Chain B, Crystal Structure Of Nitrate Reductase A, Narghi, From
Escherichia Coli
Length = 512
Score = 26.6 bits (57), Expect = 6.0
Identities = 24/117 (20%), Positives = 50/117 (42%), Gaps = 9/117 (7%)
Query: 113 WIEKLKAELRLPAGTSSKAI--VYAAKNGGGFKAHFDA----YTNLIFQIQGEKTWKLAK 166
WI K+ +L+ G + + ++A + G +++ Y NL +G K+ +A+
Sbjct: 66 WIRKINGKLQPRMGNRAMLLGKIFANPHLPGIDDYYEPFDFDYQNLHTAPEGSKSQPIAR 125
Query: 167 NENVSNPMQHYDLSEAPYYPDDLQSYW---KGDPPKEDLPDAEIVNLTPGTMLYLPR 220
++ + + + P + DDL + D +++ A M+YLPR
Sbjct: 126 PRSLITGERMAKIEKGPNWEDDLGGEFDKLAKDKNFDNIQKAMYSQFENTFMMYLPR 182
>gi|21466093|pdb|1LJ5|A Chain A, 1.8a Resolution Structure Of Latent Plasminogen Activator
Inhibitor-1(Pai-1)
gi|10835819|pdb|1DVN|A Chain A, Latent Form Of Plasminogen Activator Inhibitor-1 (Pai-1)
Length = 379
Score = 26.6 bits (57), Expect = 6.0
Identities = 15/52 (28%), Positives = 25/52 (48%), Gaps = 7/52 (13%)
Query: 176 HYDLSEAPYYPDDLQSYWKGDPPKE-------DLPDAEIVNLTPGTMLYLPR 220
+YD+ E PY+ D L + KE ++ A++++ G M LPR
Sbjct: 220 YYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPR 271
>gi|33357654|pdb|1OC0|A Chain A, Plasminogen Activator Inhibitor-1 Complex With Somatomedin
B Domain Of Vitronectin
gi|6730096|pdb|1B3K|D Chain D, Plasminogen Activator Inhibitor-1
gi|6730095|pdb|1B3K|C Chain C, Plasminogen Activator Inhibitor-1
gi|6730094|pdb|1B3K|B Chain B, Plasminogen Activator Inhibitor-1
gi|6730093|pdb|1B3K|A Chain A, Plasminogen Activator Inhibitor-1
Length = 379
Score = 26.6 bits (57), Expect = 6.0
Identities = 15/52 (28%), Positives = 25/52 (48%), Gaps = 7/52 (13%)
Query: 176 HYDLSEAPYYPDDLQSYWKGDPPKE-------DLPDAEIVNLTPGTMLYLPR 220
+YD+ E PY+ D L + KE ++ A++++ G M LPR
Sbjct: 220 YYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPR 271
>gi|4699815|pdb|9PAI|A Chain A, Cleaved Substrate Variant Of Plasminogen Activator
Inhibitor-1
Length = 379
Score = 26.6 bits (57), Expect = 6.0
Identities = 15/52 (28%), Positives = 25/52 (48%), Gaps = 7/52 (13%)
Query: 176 HYDLSEAPYYPDDLQSYWKGDPPKE-------DLPDAEIVNLTPGTMLYLPR 220
+YD+ E PY+ D L + KE ++ A++++ G M LPR
Sbjct: 220 YYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPR 271
>gi|6573637|pdb|1DB2|B Chain B, Crystal Structure Of Native Plasminogen Activator
Inhibitor- 1
gi|6573636|pdb|1DB2|A Chain A, Crystal Structure Of Native Plasminogen Activator
Inhibitor- 1
Length = 377
Score = 26.6 bits (57), Expect = 6.0
Identities = 15/52 (28%), Positives = 25/52 (48%), Gaps = 7/52 (13%)
Query: 176 HYDLSEAPYYPDDLQSYWKGDPPKE-------DLPDAEIVNLTPGTMLYLPR 220
+YD+ E PY+ D L + KE ++ A++++ G M LPR
Sbjct: 218 YYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPR 269
>gi|10120510|pdb|1DVM|D Chain D, Active Form Of Human Pai-1
gi|10120509|pdb|1DVM|C Chain C, Active Form Of Human Pai-1
gi|10120508|pdb|1DVM|B Chain B, Active Form Of Human Pai-1
gi|10120507|pdb|1DVM|A Chain A, Active Form Of Human Pai-1
Length = 379
Score = 26.6 bits (57), Expect = 6.0
Identities = 15/52 (28%), Positives = 25/52 (48%), Gaps = 7/52 (13%)
Query: 176 HYDLSEAPYYPDDLQSYWKGDPPKE-------DLPDAEIVNLTPGTMLYLPR 220
+YD+ E PY+ D L + KE ++ A++++ G M LPR
Sbjct: 220 YYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPR 271
>gi|7766820|pdb|1D9Z|A Chain A, Crystal Structure Of The Dna Repair Protein Uvrb In
Complex With Atp
Length = 657
Score = 26.6 bits (57), Expect = 6.0
Identities = 17/72 (23%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Query: 45 GFEKVRTLENVLAIYNNPVMVVGDAVIEESEGITDRFLVSPAEALEWYEKGAALEFDFTD 104
G K T+ NV+A N P +V+ + ++ P A+E++ + ++ +
Sbjct: 42 GTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFV--SYYDYYQPE 99
Query: 105 LFIPQVRRWIEK 116
++PQ +IEK
Sbjct: 100 AYVPQTDTYIEK 111
>gi|7766819|pdb|1D9X|A Chain A, Crystal Structure Of The Dna Repair Protein Uvrb
Length = 658
Score = 26.6 bits (57), Expect = 6.0
Identities = 17/72 (23%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Query: 45 GFEKVRTLENVLAIYNNPVMVVGDAVIEESEGITDRFLVSPAEALEWYEKGAALEFDFTD 104
G K T+ NV+A N P +V+ + ++ P A+E++ + ++ +
Sbjct: 42 GTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFV--SYYDYYQPE 99
Query: 105 LFIPQVRRWIEK 116
++PQ +IEK
Sbjct: 100 AYVPQTDTYIEK 111
>gi|4699714|pdb|1A7C|A Chain A, Human Plasminogen Activator Inhibitor Type-1 In Complex
With A Pentapeptide
Length = 379
Score = 26.6 bits (57), Expect = 6.0
Identities = 15/52 (28%), Positives = 25/52 (48%), Gaps = 7/52 (13%)
Query: 176 HYDLSEAPYYPDDLQSYWKGDPPKE-------DLPDAEIVNLTPGTMLYLPR 220
+YD+ E PY+ D L + KE ++ A++++ G M LPR
Sbjct: 220 YYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPR 271
>gi|48425360|pdb|1RKT|B Chain B, Crystal Structure Of Yfir, A Putative Transcriptional
Regulator From Bacillus Subtilis
gi|48425359|pdb|1RKT|A Chain A, Crystal Structure Of Yfir, A Putative Transcriptional
Regulator From Bacillus Subtilis
Length = 205
Score = 26.2 bits (56), Expect = 7.8
Identities = 11/30 (36%), Positives = 19/30 (63%)
Query: 273 HESSKSELNGYLESLIQTLSENAETLTPEQ 302
H+S + ++ YL+ L + L + A+TL P Q
Sbjct: 81 HQSVWASISSYLDELTEGLRDVADTLAPVQ 110
Database: PDB protein database
Posted date: Oct 7, 2004 12:08 AM
Number of letters in database: 4,163,319
Number of sequences in database: 18,695
Lambda K H
0.316 0.133 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,372,139
Number of Sequences: 18695
Number of extensions: 58667
Number of successful extensions: 144
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 0
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 144
Number of HSP's gapped (non-prelim): 7
length of query: 330
length of database: 4,163,319
effective HSP length: 90
effective length of query: 240
effective length of database: 2,480,769
effective search space: 595384560
effective search space used: 595384560
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 56 (26.2 bits)