FUGUE
v2.s.07 (01 Apr 2003)
#
#
#
# Search sequence(s) against fold library using
environment-specific #
# substitution tables
and structure-dependent gap penalties.
#
#
#
# Fold library and substitution tables are based on the HOMSTRAD
database. #
# http://www-cryst.bioc.cam.ac.uk/~homstrad/ #
#
#
# FUGUE server is available at:
#
# http://www-cryst.bioc.cam.ac.uk/~fugue/ #
# http://www-cryst.bioc.cam.ac.uk/~fugue/prfsearch.html #
#
#
# Citation:
#
# J. Shi, T. L. Blundell and K. Mizuguchi (2001), J Mol Biol,
310(1), 243-57 #
#
#
# N.B. Please note that Fugue has been updated (since 2nd of May
2002) and #
# consequently the recommended
z-score cut-offs used are different from #
# previous versions. The new
recommended cut-offs are shown below. #
#
#
# Size of fold library: 4610
#
# Probe sequence ID : T0192
#
# Probe sequence len : 171
#
# Probe divergence : 0.768
#
# Recommended
cutoff : ZSCORE >= 6.0 (CERTAIN
99% confidence) #
# Other cutoff : ZSCORE
>= 4.0 (LIKELY 95%
confidence) #
# Other cutoff : ZSCORE
>= 3.5 (MARGINAL 90% confidence)
#
# Other cutoff : ZSCORE
>= 2.0 (GUESS 50%
confidence) #
# Other cutoff : ZSCORE
< 2.0 (UNCERTAIN)
#
#
#
# PLEN : Profile length
#
# RAWS : Raw alignment score
#
# RVN : (Raw score)-(Raw score for NULL model)
#
# ZSCORE : Z-score normalized by sequence divergence
#
# PVZ : P-value based on Z-score jumbling
(Currently Disabled)
#
# ZORI : Original Z-score (before normalization)
#
# EVP : E-value based on profile calibration
(Currently Disabled) #
# EVF : E-value based on library search
(Currently
Disabled) #
# AL : Alignment algorithm used for
Zscore/Alignment calculation
#
# 0 --
Global, 2 -- GloLocSeq (No sequence termini gap penalty)
#
# 3 --
GloLocPrf (No profile termini gap penalty)
#
###############################################################################
#-----------------------------------------------------------------------------#
# Profile
PLEN
RAWS RVN ZSCORE PVZ
ZORI EVP
EVF AL#
#
******
#
#-----------------------------------------------------------------------------#
hs1mk4a
157
40 247 20.01 1.0E+03 22.93
1.0E+03 1.0E+03 00
hs1ghea
166
4 252 19.87 1.0E+03
22.80 1.0E+03 1.0E+03 00
hs1q2ya
140
10 218 18.17 1.0E+03 21.09
1.0E+03 1.0E+03 00
hs1i12a
154
28 235 18.05 1.0E+03 21.02
1.0E+03 1.0E+03 00
hs1qsma
150
30 236 17.17 1.0E+03 20.14
1.0E+03 1.0E+03 00
hs1p0ha
290
-274 154 14.75 1.0E+03 17.82 1.0E+03
1.0E+03 03
Acetyltransf 229
-129 181 14.42 1.0E+03 17.41 1.0E+03
1.0E+03 00
hs1on0a
152
5 190 13.65 1.0E+03
16.58 1.0E+03 1.0E+03 00
hs1nsla
173
-79 161 13.10 1.0E+03 16.04 1.0E+03
1.0E+03 00
hsd1bob
306
-52 82 10.72 1.0E+03 13.45
1.0E+03 1.0E+03 33